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September 21, 202611 min readThree new papers from Amazon Bio Discovery address bottlenecks in AI-driven antibody engineering, from benchmarking binding predictors to experimentally validating de novo design.
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August 21, 20269 min read
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July 30, 20268 min read
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Featured news
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EACL 20232023Pre-trained neural masked language models are often used for predicting a replacement token for a given sequence position, in a cloze-like task. However, this usage is restricted to predicting a single token, from a relatively small pre-trained vocabulary. Recent Sequence2Sequence pre-trained LMs like T5 do allow predicting multi-token completions, but are more expensive to train and run. We show that pre-trained
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EACL 20232023For extreme multi-label classification (XMC), existing classification-based models poorly perform for tail labels and often ignore the semantic relations among labels, like treating “Wikipedia” and “Wiki” as independent and separate labels. In this paper, we cast XMC as a generation task (XLGen), where we benefit from pre-trained text-to-text models. However, generating labels from the extremely large label
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EACL 20232023Collecting high quality conversational data can be very expensive for most applications and infeasible for others due to privacy, ethical, or similar concerns. A promising direction to tackle this problem is to generate synthetic dialogues by prompting large language models. In this work, we use a small set of expert-written conversations as in-context examples to synthesize a social conversation dataset
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European Journal of Operational Research2023This paper addresses instances of the temporal fixed-charge multi-commodity flow (tfMCF) problem that arise in a very large scale dynamic transportation application. We model the tfMCF as a discrete-time Resource Task Network (RTN) with cyclic schedule, and formulate it as a mixed-integer program. These problems are notoriously hard to solve due to their time-expanded nature, and their size renders their
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ICLR 20232023Boundary conditions (BCs) are important groups of physics-enforced constraints that are necessary for solutions of Partial Differential Equations (PDEs) to satisfy at specific spatial locations. These constraints carry important physical meaning, and guarantee the existence and the uniqueness of the PDE solution. Current neural-network based approaches that aim to solve PDEs rely only on training data to
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