Amazon Nova AI Challenge: FAQs

Including details about the 2026 Trusted Software Agent track.
General
What is the Amazon Nova AI Challenge?
The Amazon Nova AI Challenge is a university competition dedicated to accelerating the field of artificial intelligence (AI). It was created to recognize and advance students from around the globe who are shaping the future of artificial intelligence. Student teams are able to work on the latest challenges in the field of AI and build innovative solutions.
How does the Amazon Nova AI Challenge support research?
The Amazon Nova AI Challenge is a testbed for university students to experiment with and advance AI at scale. Participating teams compete to develop innovative and effective solutions to a specific challenge. Teams receive a number of forms of support, including stipends, AWS credits, and consultation and mentoring from the Amazon Nova AI Challenge team.
How do I contact Amazon if I have question about the challenge?
If you can't find an answer to your question, please email: amazon-challenge@amazon.com.
Competition details
What is the goal of this year's challenge?
The goal of the 2026 Amazon Nova AI Challenge: Trusted Software Agents track is to make effective AI systems that remain responsible and safe for all, with a focus on the task domain of agentic systems that assist users in the development of full stack web applications. The ultimate goal of the competition is to identify ways for LLM-enabled systems to handle more complex development tasks while anticipating and mitigating safety risks.
What is in scope for this competition?
The Amazon Nova AI Challenge: Trusted Software Agents track is focused on ensuring LLMs supporting AI-assisted software development remain safe, reliable, and trustworthy. For the 2026 Nova AI Challenge, we will focus on web application development as the coding task domain, with verifiable pass/fail conditions as the primary utility measure for a model developer’s system. We will continue with the “tournament-style” format used in 2025, where ten university teams — five model developer (defense) teams and five red (attack) teams compete in a series of interactive tournaments. There is an increased emphasis on advances in utility (ability to handle more complex development tasks) in parallel with safety (avoiding vulnerabilities and risk of exploits as systems handle more complex tasks) this year. Also, red teams will build systems that detect and exploit vulnerabilities in the applications built by model developer teams. 
How is this Trusted Software Agent track different than the Trusted AI track?
The Amazon Nova AI Challenge: Trusted Software Agents track is a natural extension of the Amazon Nova AI Challenge: Trusted AI track. Both focus on ensuring the safety of coding assistants. Trusted Software Agents adds additional emphasis on advances in coding utility and the domain has expanded from simpler code generation to software engineering tasks such as full stack web development. In the Trusted Software Agents track, the red teams will focus on using LLMs to identify potential vulnerabilities and exploits in applications; whereas the Trusted AI track focused on getting LLMs to generate malicious or vulnerable code.
Why should I participate?
There are multiple benefits of participating in the Amazon Nova AI Challenge: Trusted Software Agents track, including:
  1. Dynamic feedback: Teams will get the opportunity to test their systems against best-in-class competitors. Unlike static benchmarks, the challenge evaluations are dynamic and multi-turn and evolve as both sets of teams refine their systems over the course of the competition.
  2. AWS services: Participating teams will receive training, support, and access to the full suite of AWS services, with monthly AWS credits to support the cost of training and execution of their systems.
  3. IP ownership: Teams retain ownership of their work and associated IP, and are encouraged to publish their research after Amazon’s review.
  4. Stipend: Each team chosen for the Amazon Nova AI Challenge: Trusted Software Agents track will receive sponsorship in the amount of $250K. Funding is intended to support roughly two full-time students and one month of faculty time.
  5. Cash prizes: For model developer teams, the top ranked team will receive $250K and the second ranked team will receive $100K. Red teams will also receive $250K for the top ranked team and $100K for the second ranked team. All cash prizes will be divided equally among the students on the team.
When is the finals event?
The finals event will be held in September 2026. This is a closed-door event and participating teams are not invited to the Finals event.
Can we use other funding to help us participate in this challenge?
Yes, you may use other funding to support your team, subject to the terms described in the Challenge Rules. External funding must be disclosed to Amazon.
Can we publish our research from participation in the Amazon Nova AI Challenge: Trusted Software Agents track?
Yes, in fact publishing research papers as an outcome of your work on the Amazon Nova AI Challenge: Trusted Software Agents track is required for all teams participating in the competition, although teams may not publish any Amazon confidential information, as described in the Challenge Rules. The Amazon Nova AI Challenge requires all teams to submit a technical paper to be included in the challenge proceedings. Your team will not be selected for the finals if your team does not submit a technical paper for inclusion in the proceedings. Papers will be published online at the end of the competition and made publicly available through the Amazon Science website. Teams may also publish research papers in third-party publications and conferences, as long as all papers are provided to Amazon for review and approval at least two weeks before the submission deadline.
How will the tournaments be run?
The Amazon Nova AI Challenge: Trusted Software Agents track will consist of a series of interactive tournaments held from early 2026 through summer 2026. Each tournament will consist of two phases: a build phase focused on coding utility performance and a validation phase focused on application security. 

In the build phase, model developers will interact with user simulators to implement new features for an existing web application. Their success will be determined using a suite of end-to-end test cases. In the validation phase, red team systems will have the opportunity to identify and exploit vulnerabilities in the applications created in the build phase. In addition to building their coding assistants, model developers will also be tasked with building simulations of malicious users, and red teams will be tasked with building simulations of benign users. In the build phase, the coding assistants will interact with both the benign user simulators and the malicious user simulators. The red teams will not have the opportunity to find vulnerabilities in the applications resulting from interaction with their own user simulators, and model developer bots will only be matched up with malicious simulators from other defending teams. At the conclusion of each tournament, teams on each side will be ranked with respect to their performance, and the results will be shared with each team.
How will developer teams be ranked in the tournament?
Model developer teams will be ranked based on a combination of their coding utility performance and the security of the resulting applications. Coding utility performance will measure the number of tasks completed successfully across interactions with multiple user simulators (task success rate). Security performance will measure the number of resulting applications in which the red team bots do not find any vulnerabilities or exploits (defense success rate).
How will red teams be ranked in the tournament?
Red teams will be ranked on a combination of their coding utility performance and their effectiveness at identifying and exploiting vulnerabilities in applications (attack success rate). Coding utility performance will measure the number of tasks completed successfully (task success rate) as their user simulator interacts with each of the model developer teams’ coding assistants. This motivates each red team to ensure their user simulator is realistic and effective. Attack success rate for red teams will be a measure of the number of applications from the build phase in which they successfully identify or exploit vulnerabilities. In the build phase, red teams have an indirect motivation to ensure the security of the applications built through interaction with their user simulator as in doing so they preclude the ability of other red teams to score attack success points on those applications.
Eligibility
Who can apply to participate?
The Amazon Nova AI Challenge: Trusted Software Agents track is open to full-time students (undergraduate or graduate) with some exceptions (see Challenge Rules). Proof of enrollment will be required to participate.
Can I participate if I don’t attend a university?
No. The Amazon Nova AI Challenge: Trusted Software Agents track is open only to full-time enrolled university students.
Do I need to be enrolled in a university program throughout my participation in the competition?
All participating team members must remain full-time students in good standing at their university while participating in the competition.
Do I need to be a certain age?
Participants must be at or above the age of majority in the country, state, province, or jurisdiction of residence at the time of entry.
Can I enroll if a family member is an Amazon employee?
Immediate family members and household members of Amazon employees, directors, and contractors are not eligible to participate. See Challenge Rules for additional restrictions.
Teams
How many teams will be selected to participate?
All applications will be reviewed and evaluated by Amazon. Up to ten teams will be selected to compete in a tournament style competition.
How many team members can our team have?
There is no minimum or maximum number of team members. All team members must be enrolled in their university throughout their participation. All teams will receive a $250,000 grant regardless of how many members are on their team.
Can students from different universities be on the same team?
No. Teams must be composed of students attending the same university.
Can one university have more than one team?
Yes, universities may have more than one team. Multiple teams cannot have the same faculty advisor.
Can I participate on two separate teams?
No. You can only be a part of one team for the duration of the competition.
Can undergraduate and graduate students work together?
Yes, teams may be composed of undergraduate and graduate students.
Do I need a faculty advisor?
All teams must nominate a faculty advisor and include the faculty advisor’s consent in the applications.
Can there by more than one faculty advisor in a team?
Yes, there may be up to three faculty advisors per team.
What is the role of the faculty advisor?
Faculty advisors will advise students on technical direction and be a sounding board for new ideas, similar to a graduate school advisor. They will also act as the official representative from the university for this competition.
Can we add or remove team members during the competition?
During the competition, there will be a period of time during which faculty advisors may request to remove or add members to the team, subject to approval by Amazon. See Challenge Rules for details.
Can we discuss our work with faculty or students who aren’t on our team?
Only team members may work on their systems. However, the faculty advisor and other students and faculty members at your university may provide support and advice to your team and may co-author technical publications and research papers.
Application process
How do we apply to participate in the challenge?
Begin the application via YouNoodle, which will be open only during the application period.
What do we need to apply?
Once you have selected your team members, team leader, and faculty sponsor, you are ready to begin the application process. You may apply to both roles and if you do so Amazon will assign one of the two roles to your team.
Do all team members have to apply?
We prefer that the team leader submit an application on behalf of the whole team. In case a team lead has not been chosen, then any member of the team may submit an application. Each team should only submit one application, and it must include all of your team members’  and Faculty advisors’ information.
Is there an application fee?
There is no application fee.
How will teams be selected to participate?
All applications will be reviewed by a panel of experts from Amazon. Teams will be selected based on the following criteria: (1) the technical merit of the approach; (2) the novelty of the ideas; and (3) an assessment of the team’s ability to execute their plan. Please be sure to provide enough detail in your application to enable evaluation of your proposal.
Grants and prizes
Do we get a grant or other support to participate in the Amazon Nova AI Challenge: Trusted Software Agents track?
Up to ten teams will be sponsored to participate in the competition. Each sponsored team’s university will receive a $250,000 research grant to help fund the team’s participation. In addition each participating team will receive AWS credits to support the development of their system, and support from the Amazon Nova AI Challenge team.
How can the grant be spent?
The grant is intended to support two full-time students for the duration of the competition and one month of the faculty advisor’s salary. No more than 35% of the research grant may be allocated to administrative fees. Entrant Teams will be expected to use the stipend towards any uncovered costs associated with bootcamp and or summit (if any). If your team would like to use the funds in another manner, your faculty advisor must receive approval from Amazon before doing so.
What are the prizes for winning the competition?
From the evaluation at the finals event, the two top ranked model developer teams and top two ranked red teams will receive awards. The two teams placed 1st in each role (i.e., red team and developer team) will receive $250,000 each, and the two teams in 2nd place will receive $100,000 each.
US, WA, Redmond
At Amazon, we’re inventing on behalf of customers, and with Amazon Leo, we’re redefining what global connectivity looks like. Our mission is to deliver fast, affordable broadband to unserved and underserved communities around the world through a constellation of low Earth orbit (LEO) satellites. Every system we build helps connect people to education, healthcare, opportunity, and each other. As a Data Scientist, you will be responsible for developing advanced analytics and machine learning solutions for user terminals. You will develop predictive models to proactively identify possible user terminal failures in the field. You will work in a collaborative environment with a multi-disciplinary team, including constellation, RF, antenna, silicon, algorithm, and software engineers. Key job responsibilities As a Data Scientist, you will develop analytic tools for a team developing current and future user terminals. Your responsibilities include: • Develop statistical and analytical tool to enable the regression decision from on-orbit and lab measurement of user terminals • Publish documents and create compelling visualizations and presentations to communicate insights to stakeholders • Create and manage datasets for continued pre-training and supervised fine-tuning of LLMs • Develop scalable visualizations for analysis of user terminal performance • Work closely with constellation, RF, antenna, silicon, algorithm, and software engineers to root-cause the failures using data as the primary tool • Drive consensus on metrics and analysis approaches to support product development strategy Export Control Requirement: Due to applicable export control laws and regulations, candidates must be a U.S. citizen or national, U.S. permanent resident (i.e., current Green Card holder), or lawfully admitted into the U.S. as a refugee or granted asylum. A day in the life As a Data Scientist in the LEO Customer Terminal Team, you will work daily with satellite constellation, algorithm, RF, antenna, silicon, hardware, and software teams in a collaborative environment. Your focus will be using data as an intelligence source to enable design decisions for the team. About the team The LEO Customer Terminal team is responsible for developing both outdoor and indoor devices that enable customers to access internet service via the LEO satellite network. We own the entire process from early prototypes through mass production, including requirements documentation, architecture definition, hardware development, algorithm development, and all integration and verification testing.
US, NY, New York
We are seeking an Applied Scientist to lead the development of evaluation frameworks and data collection protocols for robotic capabilities. In this role, you will focus on designing how we measure, stress-test, and improve robot behavior across a wide range of real-world tasks. Your work will play a critical role in shaping how policies are validated and how high-quality datasets are generated to accelerate system performance. You will operate at the intersection of robotics, machine learning, and human-in-the-loop systems, building the infrastructure and methodologies that connect teleoperation, evaluation, and learning. This includes developing evaluation policies, defining task structures, and contributing to operator-facing interfaces that enable scalable and reliable data collection. The ideal candidate is highly experimental, systems-oriented, and comfortable working across software, robotics, and data pipelines, with a strong focus on turning ambiguous capability goals into measurable and actionable evaluation systems. Key job responsibilities - Design and implement evaluation frameworks to measure robot capabilities across structured tasks, edge cases, and real-world scenarios - Develop task definitions, success criteria, and benchmarking methodologies that enable consistent and reproducible evaluation of policies - Create and refine data collection protocols that generate high-quality, task-relevant datasets aligned with model development needs - Build and iterate on teleoperation workflows and operator interfaces to support efficient, reliable, and scalable data collection - Analyze evaluation results and collected data to identify performance gaps, failure modes, and opportunities for targeted data collection - Collaborate with engineering teams to integrate evaluation tooling, logging systems, and data pipelines into the broader robotics stack - Stay current with advances in robotics, evaluation methodologies, and human-in-the-loop learning to continuously improve internal approaches - Lead technical projects from conception through production deployment - Mentor junior scientists and engineers
US, WA, Redmond
Amazon Leo is building a constellation of thousands of low Earth orbit satellites to deliver fast, reliable internet beyond the reach of existing networks. As a Guidance, Navigation & Control engineer, you will design the algorithms, simulations, and onboard autonomy that keep every satellite precisely pointed and stable so the payload can serve customers below, and keep the fleet flying safely. This is satellite GNC with demanding pointing and performance requirements, and you will see your work go from concept to orbit on a constellation that is launching and growing today. Amazon Leo will delight customers with reliable connectivity regardless of where they are. In this role, you will: - Take your GNC algorithms from concept all the way to orbit, and stay close to them through integration, test, and on-orbit operations - Solve hard precise-pointing, payload-cueing, and fleet-autonomy problems against demanding performance requirements - Work across the full lifecycle — design, simulation, test, and flight operations — rather than a narrow slice - Join a small team of some of the top GNC engineers in the industry, building a product people will love to use This position is part of the Satellite Attitude Determination and Control team, where we own the full lifecycle of our work — from algorithm design and flight software, through lab integration, to flying our own satellites on orbit. You will design and analyze the control system and algorithms, support development of our flight hardware and software, help integrate the satellite in our labs, and operate the GNC system in flight as a constellation of satellites flows through the production line into orbit. **Export Control Requirement:** Due to applicable export control laws and regulations, candidates must be a U.S. citizen or national, U.S. permanent resident (i.e., current Green Card holder), or lawfully admitted into the U.S. as a refugee or granted asylum. Key job responsibilities - Design and analyze algorithms for state estimation, attitude determination and control, precise pointing, and payload cueing against demanding performance requirements. - Write the production C++ flight code that runs these algorithms on the satellite. Our GNC engineers own their algorithms all the way into flight software, working alongside software development engineers rather than handing prototypes off to be reimplemented by another team. - Design concepts of operation that balance pointing and payload cueing, momentum management, power, thermal, and communications across all phases of the mission, including off-nominal and contingency scenarios. - Develop momentum management strategies using reaction wheels and magnetic torquers, and help size and lay out the GNC sensor and actuator suite — star trackers, magnetometers, sun sensors, IMUs, and GPS receivers — and the algorithms that consume them. - Develop onboard autonomy, including Fault Detection, Isolation, and Recovery, so the fleet operates safely at scale with minimal intervention. - Develop and validate models and simulations of the satellite and constellation across a range of fidelity levels, including 6-DOF time-domain simulation and Monte Carlo analysis, and run hardware-in-the-loop testing to verify closed-loop performance. - Support component-level environmental testing, functional and performance checkout, and subsystem and satellite integration in our labs. - Analyze fleet telemetry in bulk and build the metrics, dashboards, and tooling that let us monitor and continuously improve pointing performance and payload operations time as the constellation grows. - Operate the GNC system on orbit — reviewing fleet data, supporting maneuvers, and resolving anomalies when on-orbit behavior diverges from the ground model. - Contribute to architecture, design, and code reviews, and document your algorithms, analyses, and results clearly. A day in the life This role spans a diverse set of problems across the spacecraft and network system. You will derive and prototype estimation and control algorithms, turn them into production flight code, and prove them out through 6-DOF and Monte Carlo simulation and hardware-in-the-loop testing in the lab. You will support satellite integration, and when something on orbit does not behave the way the ground model predicted, you will dig into fleet telemetry to find out why and drive the fix. You will own problems end to end and have the focus to go deep on each one. Because GNC sits at the center of safe flight, you will work across the whole program. The payload, power, thermal, and operations teams all depend on GNC, so you will balance their needs against your pointing and momentum budgets. To get your algorithms running reliably on the spacecraft, you will partner closely with avionics, flight software, and our embedded software development engineers. You will help the mechanical teams shape the next generation of satellite hardware, from reaction wheels to star trackers. And as satellites move from design through manufacturing into orbit, you will work alongside systems engineering and Assembly, Integration & Test. The problems are genuinely hard — demanding pointing and performance requirements, a large constellation to keep flying safely, and the chance to invent advanced capabilities that have not been built before. The work is staffed with some of the strongest engineers in the industry, and the constant collaboration across teams makes it a place to keep learning and growing. About the team Our team brings deep experience across many satellite systems and other flight vehicles, with real bench strength in both our mission and the core GNC disciplines. We design, prototype, test, iterate, and learn together, and because GNC is central to safe flight, we tend to drive Concepts of Operation and many of the system-level analyses on the program. We also have a lot of freedom. We trust our engineers to pursue the problems they face in whatever way they find best, to choose their own tools and approaches, and to own the results. If you want the autonomy to solve hard problems your way, and a team of strong engineers to do it with, you will feel at home here.
US, NY, New York
Amazon Advertising is one of Amazon's fastest growing and most profitable businesses, responsible for defining and delivering a collection of advertising products that drive discovery and sales. Our products are strategically important to our businesses driving long term growth. We deliver billions of ad impressions and millions of clicks and break fresh ground in product and technical innovations every day! Advertiser Growth Engine (AGE) team owns and builds services and applications across Amazon World-Wide Advertising that make advertising across multi-marketplaces as easy as flipping on a switch. We are focused on: (1) expanding Amazon Ads advertiser base, and (2) eliminating localization, operational, and marketplace knowledge gap barrier for Advertisers who advertise across multiple marketplaces. Our products and solutions are strategically important to enable our Retail and Marketplace businesses to drive long-term growth globally. We're looking for an experienced Applied Scientist with exceptional technical, analytical, and innovative capabilities to research, design, and create elegant machine learning solutions. The solutions will help our advertisers with multi-media and multi-lingual advertising offerings. You will use ideas from various domains of machine learning, including supervised and unsupervised methods, Deep Neural Networks, Natural Language Processing (NLP), and Computer Vision (CV) to build ML models that localizes multi-media advertising contents, including text, images and videos. You will also identify opportunities to leverage ML beyond localization, including, international expansion and global campaigns. Your work will directly impact our customers in the form of products and services used directly by our advertisers as well as our third-party integrators. As an Applied Scientist on this team, you will: - Build and deliver end-to-end machine learning solutions; build ML models and perform data analysis to deliver scalable solutions to business problems. - Perform hands-on analysis and modeling with enormous data sets to develop insights that increase traffic monetization and merchandise sales without compromising shopper experience. - Work closely with software engineers on detailed requirements to productionize the ML models you build. - Run A/B experiments that affect hundreds of millions of customers, evaluate the impact of your optimizations and communicate your results to various business stakeholders. - Establish scalable, efficient, automated processes for large-scale data analysis, machine-learning model development, model validation and serving. - Research new innovate machine learning approaches. Why you will love this opportunity: Amazon is investing heavily in building a world-class advertising business. This team defines and delivers a collection of advertising products that drive discovery and sales. Our solutions generate billions in revenue and drive long-term growth for Amazon’s Retail and Marketplace businesses. We deliver billions of ad impressions, millions of clicks daily, and break fresh ground to create world-class products. We are a highly motivated, collaborative, and fun-loving team with an entrepreneurial spirit - with a broad mandate to experiment and innovate. Impact and Career Growth: You will invent new experiences and influence customer-facing shopping experiences to help suppliers grow their retail business and the auction dynamics that leverage native advertising; this is your opportunity to work within the fastest-growing businesses across all of Amazon! Define a long-term science vision for our advertising business, driven from our customers' needs, translating that direction into specific plans for research and applied scientists, as well as engineering and product teams. This role combines science leadership, organizational ability, technical strength, product focus, and business understanding. Team video https://youtu.be/zD_6Lzw8raE
US, NY, New York
We are seeking an Applied Scientist to lead the development of evaluation frameworks and data collection protocols for robotic capabilities. In this role, you will focus on designing how we measure, stress-test, and improve robot behavior across a wide range of real-world tasks. Your work will play a critical role in shaping how policies are validated and how high-quality datasets are generated to accelerate system performance. You will operate at the intersection of robotics, machine learning, and human-in-the-loop systems, building the infrastructure and methodologies that connect teleoperation, evaluation, and learning. This includes developing evaluation policies, defining task structures, and contributing to operator-facing interfaces that enable scalable and reliable data collection. The ideal candidate is highly experimental, systems-oriented, and comfortable working across software, robotics, and data pipelines, with a strong focus on turning ambiguous capability goals into measurable and actionable evaluation systems. Key job responsibilities - Design and implement evaluation frameworks to measure robot capabilities across structured tasks, edge cases, and real-world scenarios - Develop task definitions, success criteria, and benchmarking methodologies that enable consistent and reproducible evaluation of policies - Create and refine data collection protocols that generate high-quality, task-relevant datasets aligned with model development needs - Build and iterate on teleoperation workflows and operator interfaces to support efficient, reliable, and scalable data collection - Analyze evaluation results and collected data to identify performance gaps, failure modes, and opportunities for targeted data collection - Collaborate with engineering teams to integrate evaluation tooling, logging systems, and data pipelines into the broader robotics stack - Stay current with advances in robotics, evaluation methodologies, and human-in-the-loop learning to continuously improve internal approaches - Lead technical projects from conception through production deployment - Mentor junior scientists and engineers
IL, Tel Aviv
Are you a scientist interested in pushing the state of the art in Information Retrieval, Large Language Models and Recommendation Systems? Are you interested in innovating on behalf of millions of customers, helping them accomplish their every day goals? Do you wish you had access to large datasets and tremendous computational resources? Do you want to join a team of capable scientist and engineers, building the future of e-commerce? Answer yes to any of these questions, and you will be a great fit for our team at Amazon. Our team is part of Amazon’s Personalization organization, a high-performing group that leverages Amazon’s expertise in machine learning, generative AI, large-scale data systems, and user experience design to deliver the best shopping experiences for our customers. Our team is building next-generation personalization systems powered by Large Language Models. We are tackling novel research challenges to help customers discover products they'll love - at Amazon scale and latency requirements. We are a team uniquely placed within Amazon, to have a direct window of opportunity to influence how customers will think about their shopping journey in the future. As an Applied Science Manager, you will lead a team of scientists working at the frontier of LLM-based personalization. You will set the technical vision, drive the research agenda, and ensure your team delivers production-ready solutions. You will hire, mentor, and develop world-class scientists while fostering a culture of innovation and scientific rigor. You will partner closely with engineering and product teams to translate ambitious research into customer-facing impact, and represent your team's work to senior leadership. Please visit https://www.amazon.science for more information.
US, WA, Seattle
AWS Applied AI Solutions (AAIS) is building toward a future where every business innovates with Amazon AI teammates. To get there, we build AI solutions that improve human capabilities and transform entire business functions. We create end-to-end products that surprise and delight out-of-the-box, making complex things easy and hard things possible, with no cloud experience required. We start with customers who embrace the future and build bridges to meet the rest where they are. We pursue ambitious opportunities with conviction, and we are looking for builders who share that mindset. The Team Join the next science revolution at AWS Life Sciences Applied AI Solutions where you'll work alongside world-class scientists to build AI that transforms how therapeutics are discovered, developed, and brought to patients. We're out to revolutionize how medicines are discovered, developed, and brought to patients powered by a new generation of AI. Our team tackles some of the hardest open problems at the intersection of frontier AI and life sciences. We apply biological foundation models large language models and agentic reasoning systems to life sciences problems then put them into the hands of customers as applications and managed services they can fine-tune tailor and deploy on their own data. The science challenges are deep: how do you design agentic systems that reason correctly over complex biological regulatory and clinical logic? How do you enable customers to tailor foundation models to their proprietary data and get better outputs with less effort? How do you adapt models to reason faithfully in high-stakes scientific and regulatory domains? Today we're focused on two areas. In clinical trials we're building AI that automates and optimizes regulatory and clinical development workflows. In drug design our products (including Amazon Bio Discovery) accelerate discovery by giving bench scientists AI-guided protein engineering and antibody design capabilities. We combine frontier research with production-scale delivery to put breakthrough science into the hands of customers solving humanity's hardest problems. We value scientific rigor encourage publication and support conference participation. If you want to do research that ships this is the team. The Role We are seeking an Applied Scientist to build the models and methods behind our life sciences AI products with a primary focus on clinical trial operations and agentic reasoning. You will design train and evaluate systems that reason over complex clinical and operational logic and ship them into products customers use directly. You will work closely with senior and principal scientists on well-scoped research problems own your results end to end and see your work reach production. This role combines expertise in LLM reasoning and agentic AI with applied impact in life sciences. You will work on how large language models reason plan and act in complex scientific domains while applying domain knowledge to ensure models produce scientifically valid outputs. The problems span multiple fronts: • How do you build LLM-based agentic systems that correctly reason over clinical protocols regulatory standards and complex multi-step operational workflows? • How do you evaluate agent reliability and faithfulness rigorously enough to trust in high-stakes clinical settings? • How do you develop model customization methods (fine-tuning retrieval augmentation domain adaptation) that let customers get strong results from foundation models on their own data? You will focus on clinical trial operations (agentic automation structured reasoning evaluation domain adaptation) with opportunities to contribute across drug discovery (protein engineering antibody design) as the portfolio grows. You will own end-to-end scientific solutions from research through production and your work will directly shape the tools that scientists use daily. Key job responsibilities • Design train fine-tune and evaluate LLM-based agentic systems that reason over clinical protocols regulatory standards and operational workflows • Build rigorous evaluation harnesses and benchmarks to measure agent reliability faithfulness and failure modes in high-stakes domains • Develop model customization methods (fine-tuning RLHF retrieval augmentation domain adaptation) that help customers get better outputs on their own data with less effort • Contribute to graph-based and causal modeling approaches for clinical trial operations • Partner with Life Sciences domain experts product and engineering to translate scientific challenges into shipped capabilities • Own experiments end to end: problem framing implementation evaluation iteration and hand-off to production • Publish at top-tier venues where the work supports it • Contribute to drug discovery efforts (protein engineering antibody design) as opportunities arise A day in the life • Design and run an experiment to validate a new agentic reasoning or fine-tuning method then ship it as a capability customers can use • Diagnose why a model is failing on a new class of inputs and implement a fix to unblock a delivery milestone • Build or extend an evaluation benchmark to measure how faithfully an agent reasons over clinical logic • Meet with domain experts to scope what the next model release needs to do • Review results with a senior scientist sharpen the approach and get it over the finish line • Prototype a new idea that could become the next capability in the product About the team Amazon values diverse experiences. Even if you do not meet all of the preferred qualifications and skills listed in the job description, we encourage candidates to apply. If your career is just starting, hasn't followed a traditional path, or includes alternative experiences, don't let it stop you from applying. Amazon Web Services (AWS) is the world's most comprehensive and broadly adopted cloud platform. We pioneered cloud computing and never stopped innovating — that's why customers from the most successful startups to Global 500 companies trust our robust suite of products and services to power their businesses. We value work-life harmony. Achieving success at work should never come at the expense of sacrifices at home, which is why flexible work hours and arrangements are part of our culture. When we feel supported in the workplace and at home, there's nothing we can't achieve in the cloud. Here at AWS, it's in our nature to learn and be curious. Our employee-led affinity groups foster a culture of inclusion that empower us to be proud of our differences. Ongoing events and learning experiences, including our Conversations on Race and Ethnicity and AmazeCon conferences, inspire us to never stop embracing our uniqueness. We're continuously raising our performance bar as we strive to become Earth's Best Employer. That's why you'll find endless knowledge-sharing, mentorship and other career-advancing resources here to help you develop into a better-rounded professional.
BR, SP, Sao Paulo
Do you feel the challenge and the adrenaline kick when a huge data-set stares you in the face and you know that somewhere inside are hidden very important business insights that can fundamentally alter the way top business leaders think and act? Do you enjoy presenting strong data backed insights to business leaders; insights that can topple their long held beliefs and compel them to change their direction completely? If yes, then you are the one we are looking for. We are looking to invite passionate leaders, with expertise in generate power business insights from very large datasets, on a journey where the primary aim would be to enable needle moving business impacts through statistical analysis. We are looking for leaders who can envision the design and development of analytical infrastructure which can support strategic and tactical decision-making. Those who join this high visibility team would have to navigate through significant ambiguity in defining business problems and converting them to analytical problems. This role requires additional exposure and experience to Machine Learning. Key job responsibilities Use machine learning and analytical techniques to create scalable solutions for business problems • Analyze and extract relevant information from large amounts of Amazon’s historical business data to help automate and optimize key processes • Design, development, evaluate and deploy innovative and highly scalable ml models such as risk scorecards, income models, fraud models for predictive learning in credit risk applications • Research and implement novel machine learning and statistical approaches • Work closely with software engineering teams to drive real-time model implementations and new feature creations • Work closely with business owners and operations staff to optimize various business operations • Establish scalable, efficient, automated processes for large scale data analyses, model development, model validation and model implementation • Mentor other scientists and engineers in the use of ML techniques • Innovate with the latest GenAI technology to build highly automated solutions for efficient customer promotions • Design, develop and deploy end-to-end machine learning solutions in the Amazon production environment to delight Amazon customers • Collaborate with cross-functional teams to develop comprehensive ML/statistical models that can scale to millions of customers to multiple countries Understand the credit risk data and evaluate the best ml model/ solution for dynamic business problems. About the team Brazil Payments is part of the International Emerging Stores Payments team and focuses on supporting the launch of new payment and financial products to our customers in Brazil.
BR, SP, Sao Paulo
Do you feel the challenge and the adrenaline kick when a huge data-set stares you in the face and you know that somewhere inside are hidden very important business insights that can fundamentally alter the way top business leaders think and act? Do you enjoy presenting strong data backed insights to business leaders; insights that can topple their long held beliefs and compel them to change their direction completely? If yes, then you are the one we are looking for. We are looking to invite passionate leaders, with expertise in generate power business insights from very large datasets, on a journey where the primary aim would be to enable needle moving business impacts through statistical analysis. We are looking for leaders who can envision the design and development of analytical infrastructure which can support strategic and tactical decision-making. Those who join this high visibility team would have to navigate through significant ambiguity in defining business problems and converting them to analytical problems. This role requires additional exposure and experience to Machine Learning. Key job responsibilities • Use machine learning and analytical techniques to create scalable solutions for business problems • Analyze and extract relevant information from large amounts of Amazon’s historical business data to help automate and optimize key processes • Design, development, evaluate and deploy innovative and highly scalable models for predictive learning • Research and implement novel machine learning and statistical approaches • Work closely with software engineering teams to drive real-time model implementations and new feature creations • Work closely with business owners and operations staff to optimize various business operations • Establish scalable, efficient, automated processes for large scale data analyses, model development, model validation and model implementation • Mentor other scientists and engineers in the use of ML techniques • Innovate with the latest GenAI technology to build highly automated solutions for efficient customer promotions • Design, develop and deploy end-to-end machine learning solutions in the Amazon production environment to delight Amazon customers • Collaborate with cross-functional teams to develop comprehensive ML/statistical models that can scale to millions of customers to multiple countries About the team Brazil Payments is part of the International Emerging Stores Payments team and focuses on supporting the launch of new payment and financial products to our customers in Brazil.
BR, SP, Sao Paulo
Do you feel the challenge and the adrenaline kick when a huge data-set stares you in the face and you know that somewhere inside are hidden very important business insights that can fundamentally alter the way top business leaders think and act? Do you enjoy presenting strong data backed insights to business leaders; insights that can topple their long held beliefs and compel them to change their direction completely? If yes, then you are the one we are looking for. We are looking to invite passionate leaders, with expertise in generate power business insights from very large datasets, on a journey where the primary aim would be to enable needle moving business impacts through statistical analysis. We are looking for leaders who can envision the design and development of analytical infrastructure which can support strategic and tactical decision-making. Those who join this high visibility team would have to navigate through significant ambiguity in defining business problems and converting them to analytical problems. This role requires additional exposure and experience to Machine Learning. Key job responsibilities Use machine learning and analytical techniques to create scalable solutions for business problems • Analyze and extract relevant information from large amounts of Amazon’s historical business data to help automate and optimize key processes • Design, development, evaluate and deploy innovative and highly scalable ml models such as risk scorecards, income models, fraud models for predictive learning in credit risk applications • Research and implement novel machine learning and statistical approaches • Work closely with software engineering teams to drive real-time model implementations and new feature creations • Work closely with business owners and operations staff to optimize various business operations • Establish scalable, efficient, automated processes for large scale data analyses, model development, model validation and model implementation • Mentor other scientists and engineers in the use of ML techniques • Innovate with the latest GenAI technology to build highly automated solutions for efficient customer promotions • Design, develop and deploy end-to-end machine learning solutions in the Amazon production environment to delight Amazon customers • Collaborate with cross-functional teams to develop comprehensive ML/statistical models that can scale to millions of customers to multiple countries Understand the credit risk data and evaluate the best ml model/ solution for dynamic business problems. About the team Brazil Payments is part of the International Emerging Stores Payments team and focuses on supporting the launch of new payment and financial products to our customers in Brazil.