Alexa enters the “age of self”

More-autonomous machine learning systems will make Alexa more self-aware, self-learning, and self-service.

Alexa launched in 2014, and in the more than six years since, we’ve been making good on our promise to make Alexa smarter every day. In addition to foundational improvements in Alexa’s core AI technologies, such as speech recognition and natural-language-understanding systems, Alexa scientists have developed technologies that continue to delight our customers, such as whispered speech and Alexa’s new live translation service.

Prem Natarajan, Alexa AI vice president of natural understanding, giving a presentation
Prem Natarajan, Alexa AI vice president of natural understanding, at a conference in 2018.

But some of the technologies we’ve begun to introduce, together with others we’re now investigating, are harbingers of a step change in Alexa’s development — and in the field of AI itself. Collectively, these technologies will bring a new level of generalizability and autonomy to both the Alexa voice service and the tools available to Alexa developers, ushering in what I like to think of as a new “age of self” in artificial intelligence, an age in which AI systems such as Alexa become more self-aware and more self-learning, and in which they lend themselves to self-service by experienced developers and even end users.

By self-awareness, I mean the ability to maintain an awareness of ambient state (e.g., time of day, thermostat readings, and recent actions) and to employ commonsense reasoning to make inferences that reflect that awareness and prior/world knowledge. Alexa hunches can already recognize anomalies in customers’ daily routines and suggest corrections — noticing that a light was left on at night and offering to turn it off, for instance. Powered by commonsense reasoning, self-awareness goes further: for instance, if a customer turns on the television five minutes before the kids’ soccer practice is scheduled to end, an AI of the future might infer that the customer needs a reminder about pickup.

Smart home.png
In the "age of self", AIs will be able to infer customers’ implicit intentions from observable temporal patterns, such as interactions with smart-home devices like thermostats, door locks, and lights.

Self-learning is Alexa’s ability to improve and expand its capabilities without human intervention. And like self-awareness, self-learning employs reasoning: for example, does the customer’s response to an action indicate dissatisfaction with that action? Similarly, when a customer issues an unfamiliar command, a truly self-learning Alexa would be able to infer what it might mean — perhaps by searching the web or exploring a knowledge base — and suggest possibilities.

Self-service means, essentially, the democratization of AI. Alexa customers with no programming experience should be able to customize Alexa’s services and even create new Alexa capabilities, and skill developers without machine learning experience should be able to build complex yet robust conversational skills. Colloquially, these are the conversational-AI equivalents of no-code and low-code development environments.

To be clear, the age of self is not yet upon us, and its dawning will require the maturation of technologies still under development, at Amazon and elsewhere. But some of Alexa’s recently launched capabilities herald a lightening in the Eastern sky.

Self-awareness

In 2018, we launched Alexa hunches for the smart home, with Alexa suggesting actions to take in response to anomalous sensor data. By early 2021, the science has advanced adequately for us to launch an opt-in service in which Alexa can take action immediately and automatically. In the meantime, we’ve also been working to expand hunches to Alexa services other than the smart home.

Technologies will bring a new level of generalizability and autonomy to both the Alexa voice service and the tools available to Alexa developers, ushering in what I like to think of as a new 'age of self' in artificial intelligence.
Prem Natarajan

But commonsense reasoning requires something more — the ability to infer customers’ implicit intentions from observable temporal patterns. For instance, what does it mean if the customer turns down the thermostat, turns out the lights, locks the front door, and opens the garage? What if the customer initiates an interaction with a query like “Alexa, what’s playing at Rolling Hills Cine Plaza?”

In 2020, we took steps toward commonsense reasoning with a new Alexa function that can infer a customer’s latent goal— the ultimate aim that lies behind a sequence of requests. When a customer asks for the weather at the beach, for instance, Alexa might use that query, in combination with other contextual information, to infer that the customer may be interested in a trip to the beach. Alexa could then offer the current driving time to the beach.

To retrieve that information, Alexa has to know to map the location of the weather request to the destination variable in the route-planning function. This illustrates another aspect of self-awareness: the ability to track information across contexts.

That ability is at the core of the night-out experience we’ve developed, which engages the customer in a multiturn conversation to plan a complete night out, from buying movie tickets to making restaurant and ride-share reservations. The night-out experience tracks times and locations across skills, revising them on the fly as customers evaluate different options. To build the experience, we leveraged the machinery of Alexa Conversations, a service that enables developers to quickly and easily create dialogue-driven skills, and we drew on our growing body of research on dialogue state tracking.

Slot_tracking.png._CB436837753_.png
Dialogue states at several successive dialogue turns

Self-awareness, however, includes an understanding not only of the conversational context but also of the customer’s physical context. In 2020, we demonstrated natural turn-taking on Alexa-enabled devices with cameras. When multiple speakers are engaging with Alexa, Alexa can use visual cues to distinguish between speech the customers are directing at each other and speech they’re directing at Alexa. In ongoing work, we’re working to expand this functionality to devices without cameras, by relying solely on acoustic and linguistic signals.

Finally, self-awareness also entails the capacity for self-explanation. Today, most machine learning models are black boxes; even their creators have no idea how they’re doing what they do. That uncertainty has turned explainable or interpretable AI into a popular research topic.

Amazon actively publishes on explainable-AI topics. In addition, the Alexa Fund, an Amazon venture capital investment program, invested in fiddler.ai, a startup that uses techniques based on the game-theoretical concept of Shapley values to do explainable AI.

Self-learning

Historically, the AI development cycle has involved collection of data, annotation of that data, and retraining of models on the newly annotated data — all of which add up to a laborious process.

In 2019, we launched Alexa’s self-learning system, which automatically learns to correct errors — both customer errors and errors in Alexa’s language-understanding models — without human involvement. The system relies on implicit signals that a request was improperly handled, as when a customer interrupts a response and rephrases the same request.

Absorbing-Markov-chain models for three different sequences of utterances
Alexa's self-learning system models customer interactions with Alexa as sequences of states; different customer utterances (u0, u1, u2) can correspond to the same state (h0). The final state of a sequence, known as the "absorbing state", indicates the success (checkmark) or failure (X) of a transaction.
Stacy Reilly

Currently, that fully automatic system is correcting 15% of defects. But those are defects that occur across a spectrum of users; only when enough people implicitly identify the same flaw does the system address it. We are working to adapt the same machinery to individual customers’ preferences — so that, for instance, Alexa can learn that when a particular customer asks for the song “Wow”, she means not the Post Malone hit from 2019 but the 1978 Kate Bush song.

Customers today also have the option of explicitly teaching Alexa their preferences. In the fall of 2020, we launched interactive teaching by customers, a capability that enables customers to instruct Alexa how they want certain requests to be handled. For instance, the customer can teach Alexa that the command “reading mode” means lights turned all the way up, while “movie mode” means only twenty percent up.

Self-service

Interactive teaching is also an early example of how Alexa is enabling more self-service. It extends prior Alexa features, like blueprints, which let customers build their own simple skills from preexisting templates, and routines, which let customers chain together sequences of actions under individual commands.

In March 2021, we announced the public release of Alexa Conversations, which allows developers to create dialogue-driven skills by uploading sample dialogues. Alexa Conversations’ sophisticated machine learning models use those dialogues as templates for generating larger corpora of synthetic training data. From that data, Alexa Conversations automatically trains a machine learning model.

Alexa Conversations does, however, require the developer to specify the set of entities that the new model should act upon and an application programming interface for the skill. So while it requires little familiarity with machine learning, it assumes some programming experience. 

ambiguous_slots.gif._CB438712971_.gif
An Alexa feature known as catalogue value suggestions suggests entity names to skill developers on the basis of their "embeddings", or locations in a representational space. If the embeddings of values (such as bird, dog, or cat) for a particular entity type are close enough (dotted circles) to their averages (solid circle and square), the system suggests new entity names; otherwise, it concludes that suggestions would be unproductive.
Animation by Nick Little

We are steadily chipping away at even that requirement, by making development for Alexa easier and more intuitive. As Alexa’s repertory of skills grows, for instance, entities are frequently reused, and we already have systems that can inform developers about entity types that they might not have thought to add to their skills. This is a step toward a self-service model in which developers no longer have to provide exhaustive lists of entities — or, in some cases, any entities at all.

Another technique that makes it easier to build machine learning models is few-shot learning, in which an existing model is generalized to a related task using only a handful of new training examples. This is an active area of research at Alexa: earlier this year, for example, we presented a paper at the Spoken Language Technologies conference that described a new approach to few-shot learning for natural-language-understanding tasks. Compared to its predecessors, our approach reduced the error rate on certain natural-language-understanding tasks by up to 12.4%, when each model was trained on only 10 examples.

These advances, along with the others reported on Amazon Science, demonstrate that the Alexa AI team continues to accelerate its pace of invention. More exciting announcements lie just over the horizon. I’ll be stopping back here every once in a while to update you on Alexa’s journey into the age of self.

Research areas

Related content

  • Meiqi Sun
    April 20, 2026
    Large language models today can solve algebra, pass academic benchmarks, and generate highly structured chain-of-thought explanations. In text-only settings, they often feel startlingly intelligent — methodical, articulate, even strategic. But place those models inside an interactive environment — ask them to click buttons, scroll pages, fill out forms, and submit answers — and their behavior changes. Their careful reasoning falters. They guess where they once deduced. They adhere to templates and produce limited procedural narration: stating what they see and what they will click next, without first forming a structured plan and acting in accordance with plan. It’s as if part of their intelligence has quietly gone offline the moment the cursor appears.
    Machine learning
  • Splitting the “separation kernel” off from the rest of the Nitro security system and using only a subset of the Rust programming language to code it enabled its formal verification.
  • Amazon Research Awards team
    August 5, 2026
    Amazon announces 34 recipients of the Build on Trainium program, a $110 million credit initiative supporting AI research at 30 universities including Stanford, UC Berkeley, UIUC, UCLA, CMU, and MIT, with a focus on Responsible AI.
US, WA, Redmond
At Amazon, we’re inventing on behalf of customers, and with Amazon Leo, we’re redefining what global connectivity looks like. Our mission is to deliver fast, affordable broadband to unserved and underserved communities around the world through a constellation of low Earth orbit (LEO) satellites. Every system we build helps connect people to education, healthcare, opportunity, and each other. As a Data Scientist, you will be responsible for developing advanced analytics and machine learning solutions for user terminals. You will develop predictive models to proactively identify possible user terminal failures in the field. You will work in a collaborative environment with a multi-disciplinary team, including constellation, RF, antenna, silicon, algorithm, and software engineers. Key job responsibilities As a Data Scientist, you will develop analytic tools for a team developing current and future user terminals. Your responsibilities include: • Develop statistical and analytical tool to enable the regression decision from on-orbit and lab measurement of user terminals • Publish documents and create compelling visualizations and presentations to communicate insights to stakeholders • Create and manage datasets for continued pre-training and supervised fine-tuning of LLMs • Develop scalable visualizations for analysis of user terminal performance • Work closely with constellation, RF, antenna, silicon, algorithm, and software engineers to root-cause the failures using data as the primary tool • Drive consensus on metrics and analysis approaches to support product development strategy Export Control Requirement: Due to applicable export control laws and regulations, candidates must be a U.S. citizen or national, U.S. permanent resident (i.e., current Green Card holder), or lawfully admitted into the U.S. as a refugee or granted asylum. A day in the life As a Data Scientist in the LEO Customer Terminal Team, you will work daily with satellite constellation, algorithm, RF, antenna, silicon, hardware, and software teams in a collaborative environment. Your focus will be using data as an intelligence source to enable design decisions for the team. About the team The LEO Customer Terminal team is responsible for developing both outdoor and indoor devices that enable customers to access internet service via the LEO satellite network. We own the entire process from early prototypes through mass production, including requirements documentation, architecture definition, hardware development, algorithm development, and all integration and verification testing.
US, NY, New York
We are seeking an Applied Scientist to lead the development of evaluation frameworks and data collection protocols for robotic capabilities. In this role, you will focus on designing how we measure, stress-test, and improve robot behavior across a wide range of real-world tasks. Your work will play a critical role in shaping how policies are validated and how high-quality datasets are generated to accelerate system performance. You will operate at the intersection of robotics, machine learning, and human-in-the-loop systems, building the infrastructure and methodologies that connect teleoperation, evaluation, and learning. This includes developing evaluation policies, defining task structures, and contributing to operator-facing interfaces that enable scalable and reliable data collection. The ideal candidate is highly experimental, systems-oriented, and comfortable working across software, robotics, and data pipelines, with a strong focus on turning ambiguous capability goals into measurable and actionable evaluation systems. Key job responsibilities - Design and implement evaluation frameworks to measure robot capabilities across structured tasks, edge cases, and real-world scenarios - Develop task definitions, success criteria, and benchmarking methodologies that enable consistent and reproducible evaluation of policies - Create and refine data collection protocols that generate high-quality, task-relevant datasets aligned with model development needs - Build and iterate on teleoperation workflows and operator interfaces to support efficient, reliable, and scalable data collection - Analyze evaluation results and collected data to identify performance gaps, failure modes, and opportunities for targeted data collection - Collaborate with engineering teams to integrate evaluation tooling, logging systems, and data pipelines into the broader robotics stack - Stay current with advances in robotics, evaluation methodologies, and human-in-the-loop learning to continuously improve internal approaches - Lead technical projects from conception through production deployment - Mentor junior scientists and engineers
US, WA, Redmond
Amazon Leo is building a constellation of thousands of low Earth orbit satellites to deliver fast, reliable internet beyond the reach of existing networks. As a Guidance, Navigation & Control engineer, you will design the algorithms, simulations, and onboard autonomy that keep every satellite precisely pointed and stable so the payload can serve customers below, and keep the fleet flying safely. This is satellite GNC with demanding pointing and performance requirements, and you will see your work go from concept to orbit on a constellation that is launching and growing today. Amazon Leo will delight customers with reliable connectivity regardless of where they are. In this role, you will: - Take your GNC algorithms from concept all the way to orbit, and stay close to them through integration, test, and on-orbit operations - Solve hard precise-pointing, payload-cueing, and fleet-autonomy problems against demanding performance requirements - Work across the full lifecycle — design, simulation, test, and flight operations — rather than a narrow slice - Join a small team of some of the top GNC engineers in the industry, building a product people will love to use This position is part of the Satellite Attitude Determination and Control team, where we own the full lifecycle of our work — from algorithm design and flight software, through lab integration, to flying our own satellites on orbit. You will design and analyze the control system and algorithms, support development of our flight hardware and software, help integrate the satellite in our labs, and operate the GNC system in flight as a constellation of satellites flows through the production line into orbit. **Export Control Requirement:** Due to applicable export control laws and regulations, candidates must be a U.S. citizen or national, U.S. permanent resident (i.e., current Green Card holder), or lawfully admitted into the U.S. as a refugee or granted asylum. Key job responsibilities - Design and analyze algorithms for state estimation, attitude determination and control, precise pointing, and payload cueing against demanding performance requirements. - Write the production C++ flight code that runs these algorithms on the satellite. Our GNC engineers own their algorithms all the way into flight software, working alongside software development engineers rather than handing prototypes off to be reimplemented by another team. - Design concepts of operation that balance pointing and payload cueing, momentum management, power, thermal, and communications across all phases of the mission, including off-nominal and contingency scenarios. - Develop momentum management strategies using reaction wheels and magnetic torquers, and help size and lay out the GNC sensor and actuator suite — star trackers, magnetometers, sun sensors, IMUs, and GPS receivers — and the algorithms that consume them. - Develop onboard autonomy, including Fault Detection, Isolation, and Recovery, so the fleet operates safely at scale with minimal intervention. - Develop and validate models and simulations of the satellite and constellation across a range of fidelity levels, including 6-DOF time-domain simulation and Monte Carlo analysis, and run hardware-in-the-loop testing to verify closed-loop performance. - Support component-level environmental testing, functional and performance checkout, and subsystem and satellite integration in our labs. - Analyze fleet telemetry in bulk and build the metrics, dashboards, and tooling that let us monitor and continuously improve pointing performance and payload operations time as the constellation grows. - Operate the GNC system on orbit — reviewing fleet data, supporting maneuvers, and resolving anomalies when on-orbit behavior diverges from the ground model. - Contribute to architecture, design, and code reviews, and document your algorithms, analyses, and results clearly. A day in the life This role spans a diverse set of problems across the spacecraft and network system. You will derive and prototype estimation and control algorithms, turn them into production flight code, and prove them out through 6-DOF and Monte Carlo simulation and hardware-in-the-loop testing in the lab. You will support satellite integration, and when something on orbit does not behave the way the ground model predicted, you will dig into fleet telemetry to find out why and drive the fix. You will own problems end to end and have the focus to go deep on each one. Because GNC sits at the center of safe flight, you will work across the whole program. The payload, power, thermal, and operations teams all depend on GNC, so you will balance their needs against your pointing and momentum budgets. To get your algorithms running reliably on the spacecraft, you will partner closely with avionics, flight software, and our embedded software development engineers. You will help the mechanical teams shape the next generation of satellite hardware, from reaction wheels to star trackers. And as satellites move from design through manufacturing into orbit, you will work alongside systems engineering and Assembly, Integration & Test. The problems are genuinely hard — demanding pointing and performance requirements, a large constellation to keep flying safely, and the chance to invent advanced capabilities that have not been built before. The work is staffed with some of the strongest engineers in the industry, and the constant collaboration across teams makes it a place to keep learning and growing. About the team Our team brings deep experience across many satellite systems and other flight vehicles, with real bench strength in both our mission and the core GNC disciplines. We design, prototype, test, iterate, and learn together, and because GNC is central to safe flight, we tend to drive Concepts of Operation and many of the system-level analyses on the program. We also have a lot of freedom. We trust our engineers to pursue the problems they face in whatever way they find best, to choose their own tools and approaches, and to own the results. If you want the autonomy to solve hard problems your way, and a team of strong engineers to do it with, you will feel at home here.
US, NY, New York
Amazon Advertising is one of Amazon's fastest growing and most profitable businesses, responsible for defining and delivering a collection of advertising products that drive discovery and sales. Our products are strategically important to our businesses driving long term growth. We deliver billions of ad impressions and millions of clicks and break fresh ground in product and technical innovations every day! Advertiser Growth Engine (AGE) team owns and builds services and applications across Amazon World-Wide Advertising that make advertising across multi-marketplaces as easy as flipping on a switch. We are focused on: (1) expanding Amazon Ads advertiser base, and (2) eliminating localization, operational, and marketplace knowledge gap barrier for Advertisers who advertise across multiple marketplaces. Our products and solutions are strategically important to enable our Retail and Marketplace businesses to drive long-term growth globally. We're looking for an experienced Applied Scientist with exceptional technical, analytical, and innovative capabilities to research, design, and create elegant machine learning solutions. The solutions will help our advertisers with multi-media and multi-lingual advertising offerings. You will use ideas from various domains of machine learning, including supervised and unsupervised methods, Deep Neural Networks, Natural Language Processing (NLP), and Computer Vision (CV) to build ML models that localizes multi-media advertising contents, including text, images and videos. You will also identify opportunities to leverage ML beyond localization, including, international expansion and global campaigns. Your work will directly impact our customers in the form of products and services used directly by our advertisers as well as our third-party integrators. As an Applied Scientist on this team, you will: - Build and deliver end-to-end machine learning solutions; build ML models and perform data analysis to deliver scalable solutions to business problems. - Perform hands-on analysis and modeling with enormous data sets to develop insights that increase traffic monetization and merchandise sales without compromising shopper experience. - Work closely with software engineers on detailed requirements to productionize the ML models you build. - Run A/B experiments that affect hundreds of millions of customers, evaluate the impact of your optimizations and communicate your results to various business stakeholders. - Establish scalable, efficient, automated processes for large-scale data analysis, machine-learning model development, model validation and serving. - Research new innovate machine learning approaches. Why you will love this opportunity: Amazon is investing heavily in building a world-class advertising business. This team defines and delivers a collection of advertising products that drive discovery and sales. Our solutions generate billions in revenue and drive long-term growth for Amazon’s Retail and Marketplace businesses. We deliver billions of ad impressions, millions of clicks daily, and break fresh ground to create world-class products. We are a highly motivated, collaborative, and fun-loving team with an entrepreneurial spirit - with a broad mandate to experiment and innovate. Impact and Career Growth: You will invent new experiences and influence customer-facing shopping experiences to help suppliers grow their retail business and the auction dynamics that leverage native advertising; this is your opportunity to work within the fastest-growing businesses across all of Amazon! Define a long-term science vision for our advertising business, driven from our customers' needs, translating that direction into specific plans for research and applied scientists, as well as engineering and product teams. This role combines science leadership, organizational ability, technical strength, product focus, and business understanding. Team video https://youtu.be/zD_6Lzw8raE
US, NY, New York
We are seeking an Applied Scientist to lead the development of evaluation frameworks and data collection protocols for robotic capabilities. In this role, you will focus on designing how we measure, stress-test, and improve robot behavior across a wide range of real-world tasks. Your work will play a critical role in shaping how policies are validated and how high-quality datasets are generated to accelerate system performance. You will operate at the intersection of robotics, machine learning, and human-in-the-loop systems, building the infrastructure and methodologies that connect teleoperation, evaluation, and learning. This includes developing evaluation policies, defining task structures, and contributing to operator-facing interfaces that enable scalable and reliable data collection. The ideal candidate is highly experimental, systems-oriented, and comfortable working across software, robotics, and data pipelines, with a strong focus on turning ambiguous capability goals into measurable and actionable evaluation systems. Key job responsibilities - Design and implement evaluation frameworks to measure robot capabilities across structured tasks, edge cases, and real-world scenarios - Develop task definitions, success criteria, and benchmarking methodologies that enable consistent and reproducible evaluation of policies - Create and refine data collection protocols that generate high-quality, task-relevant datasets aligned with model development needs - Build and iterate on teleoperation workflows and operator interfaces to support efficient, reliable, and scalable data collection - Analyze evaluation results and collected data to identify performance gaps, failure modes, and opportunities for targeted data collection - Collaborate with engineering teams to integrate evaluation tooling, logging systems, and data pipelines into the broader robotics stack - Stay current with advances in robotics, evaluation methodologies, and human-in-the-loop learning to continuously improve internal approaches - Lead technical projects from conception through production deployment - Mentor junior scientists and engineers
IL, Tel Aviv
Are you a scientist interested in pushing the state of the art in Information Retrieval, Large Language Models and Recommendation Systems? Are you interested in innovating on behalf of millions of customers, helping them accomplish their every day goals? Do you wish you had access to large datasets and tremendous computational resources? Do you want to join a team of capable scientist and engineers, building the future of e-commerce? Answer yes to any of these questions, and you will be a great fit for our team at Amazon. Our team is part of Amazon’s Personalization organization, a high-performing group that leverages Amazon’s expertise in machine learning, generative AI, large-scale data systems, and user experience design to deliver the best shopping experiences for our customers. Our team is building next-generation personalization systems powered by Large Language Models. We are tackling novel research challenges to help customers discover products they'll love - at Amazon scale and latency requirements. We are a team uniquely placed within Amazon, to have a direct window of opportunity to influence how customers will think about their shopping journey in the future. As an Applied Science Manager, you will lead a team of scientists working at the frontier of LLM-based personalization. You will set the technical vision, drive the research agenda, and ensure your team delivers production-ready solutions. You will hire, mentor, and develop world-class scientists while fostering a culture of innovation and scientific rigor. You will partner closely with engineering and product teams to translate ambitious research into customer-facing impact, and represent your team's work to senior leadership. Please visit https://www.amazon.science for more information.
US, WA, Seattle
AWS Applied AI Solutions (AAIS) is building toward a future where every business innovates with Amazon AI teammates. To get there, we build AI solutions that improve human capabilities and transform entire business functions. We create end-to-end products that surprise and delight out-of-the-box, making complex things easy and hard things possible, with no cloud experience required. We start with customers who embrace the future and build bridges to meet the rest where they are. We pursue ambitious opportunities with conviction, and we are looking for builders who share that mindset. The Team Join the next science revolution at AWS Life Sciences Applied AI Solutions where you'll work alongside world-class scientists to build AI that transforms how therapeutics are discovered, developed, and brought to patients. We're out to revolutionize how medicines are discovered, developed, and brought to patients powered by a new generation of AI. Our team tackles some of the hardest open problems at the intersection of frontier AI and life sciences. We apply biological foundation models large language models and agentic reasoning systems to life sciences problems then put them into the hands of customers as applications and managed services they can fine-tune tailor and deploy on their own data. The science challenges are deep: how do you design agentic systems that reason correctly over complex biological regulatory and clinical logic? How do you enable customers to tailor foundation models to their proprietary data and get better outputs with less effort? How do you adapt models to reason faithfully in high-stakes scientific and regulatory domains? Today we're focused on two areas. In clinical trials we're building AI that automates and optimizes regulatory and clinical development workflows. In drug design our products (including Amazon Bio Discovery) accelerate discovery by giving bench scientists AI-guided protein engineering and antibody design capabilities. We combine frontier research with production-scale delivery to put breakthrough science into the hands of customers solving humanity's hardest problems. We value scientific rigor encourage publication and support conference participation. If you want to do research that ships this is the team. The Role We are seeking an Applied Scientist to build the models and methods behind our life sciences AI products with a primary focus on clinical trial operations and agentic reasoning. You will design train and evaluate systems that reason over complex clinical and operational logic and ship them into products customers use directly. You will work closely with senior and principal scientists on well-scoped research problems own your results end to end and see your work reach production. This role combines expertise in LLM reasoning and agentic AI with applied impact in life sciences. You will work on how large language models reason plan and act in complex scientific domains while applying domain knowledge to ensure models produce scientifically valid outputs. The problems span multiple fronts: • How do you build LLM-based agentic systems that correctly reason over clinical protocols regulatory standards and complex multi-step operational workflows? • How do you evaluate agent reliability and faithfulness rigorously enough to trust in high-stakes clinical settings? • How do you develop model customization methods (fine-tuning retrieval augmentation domain adaptation) that let customers get strong results from foundation models on their own data? You will focus on clinical trial operations (agentic automation structured reasoning evaluation domain adaptation) with opportunities to contribute across drug discovery (protein engineering antibody design) as the portfolio grows. You will own end-to-end scientific solutions from research through production and your work will directly shape the tools that scientists use daily. Key job responsibilities • Design train fine-tune and evaluate LLM-based agentic systems that reason over clinical protocols regulatory standards and operational workflows • Build rigorous evaluation harnesses and benchmarks to measure agent reliability faithfulness and failure modes in high-stakes domains • Develop model customization methods (fine-tuning RLHF retrieval augmentation domain adaptation) that help customers get better outputs on their own data with less effort • Contribute to graph-based and causal modeling approaches for clinical trial operations • Partner with Life Sciences domain experts product and engineering to translate scientific challenges into shipped capabilities • Own experiments end to end: problem framing implementation evaluation iteration and hand-off to production • Publish at top-tier venues where the work supports it • Contribute to drug discovery efforts (protein engineering antibody design) as opportunities arise A day in the life • Design and run an experiment to validate a new agentic reasoning or fine-tuning method then ship it as a capability customers can use • Diagnose why a model is failing on a new class of inputs and implement a fix to unblock a delivery milestone • Build or extend an evaluation benchmark to measure how faithfully an agent reasons over clinical logic • Meet with domain experts to scope what the next model release needs to do • Review results with a senior scientist sharpen the approach and get it over the finish line • Prototype a new idea that could become the next capability in the product About the team Amazon values diverse experiences. Even if you do not meet all of the preferred qualifications and skills listed in the job description, we encourage candidates to apply. If your career is just starting, hasn't followed a traditional path, or includes alternative experiences, don't let it stop you from applying. Amazon Web Services (AWS) is the world's most comprehensive and broadly adopted cloud platform. We pioneered cloud computing and never stopped innovating — that's why customers from the most successful startups to Global 500 companies trust our robust suite of products and services to power their businesses. We value work-life harmony. Achieving success at work should never come at the expense of sacrifices at home, which is why flexible work hours and arrangements are part of our culture. When we feel supported in the workplace and at home, there's nothing we can't achieve in the cloud. Here at AWS, it's in our nature to learn and be curious. Our employee-led affinity groups foster a culture of inclusion that empower us to be proud of our differences. Ongoing events and learning experiences, including our Conversations on Race and Ethnicity and AmazeCon conferences, inspire us to never stop embracing our uniqueness. We're continuously raising our performance bar as we strive to become Earth's Best Employer. That's why you'll find endless knowledge-sharing, mentorship and other career-advancing resources here to help you develop into a better-rounded professional.
BR, SP, Sao Paulo
Do you feel the challenge and the adrenaline kick when a huge data-set stares you in the face and you know that somewhere inside are hidden very important business insights that can fundamentally alter the way top business leaders think and act? Do you enjoy presenting strong data backed insights to business leaders; insights that can topple their long held beliefs and compel them to change their direction completely? If yes, then you are the one we are looking for. We are looking to invite passionate leaders, with expertise in generate power business insights from very large datasets, on a journey where the primary aim would be to enable needle moving business impacts through statistical analysis. We are looking for leaders who can envision the design and development of analytical infrastructure which can support strategic and tactical decision-making. Those who join this high visibility team would have to navigate through significant ambiguity in defining business problems and converting them to analytical problems. This role requires additional exposure and experience to Machine Learning. Key job responsibilities Use machine learning and analytical techniques to create scalable solutions for business problems • Analyze and extract relevant information from large amounts of Amazon’s historical business data to help automate and optimize key processes • Design, development, evaluate and deploy innovative and highly scalable ml models such as risk scorecards, income models, fraud models for predictive learning in credit risk applications • Research and implement novel machine learning and statistical approaches • Work closely with software engineering teams to drive real-time model implementations and new feature creations • Work closely with business owners and operations staff to optimize various business operations • Establish scalable, efficient, automated processes for large scale data analyses, model development, model validation and model implementation • Mentor other scientists and engineers in the use of ML techniques • Innovate with the latest GenAI technology to build highly automated solutions for efficient customer promotions • Design, develop and deploy end-to-end machine learning solutions in the Amazon production environment to delight Amazon customers • Collaborate with cross-functional teams to develop comprehensive ML/statistical models that can scale to millions of customers to multiple countries Understand the credit risk data and evaluate the best ml model/ solution for dynamic business problems. About the team Brazil Payments is part of the International Emerging Stores Payments team and focuses on supporting the launch of new payment and financial products to our customers in Brazil.
BR, SP, Sao Paulo
Do you feel the challenge and the adrenaline kick when a huge data-set stares you in the face and you know that somewhere inside are hidden very important business insights that can fundamentally alter the way top business leaders think and act? Do you enjoy presenting strong data backed insights to business leaders; insights that can topple their long held beliefs and compel them to change their direction completely? If yes, then you are the one we are looking for. We are looking to invite passionate leaders, with expertise in generate power business insights from very large datasets, on a journey where the primary aim would be to enable needle moving business impacts through statistical analysis. We are looking for leaders who can envision the design and development of analytical infrastructure which can support strategic and tactical decision-making. Those who join this high visibility team would have to navigate through significant ambiguity in defining business problems and converting them to analytical problems. This role requires additional exposure and experience to Machine Learning. Key job responsibilities • Use machine learning and analytical techniques to create scalable solutions for business problems • Analyze and extract relevant information from large amounts of Amazon’s historical business data to help automate and optimize key processes • Design, development, evaluate and deploy innovative and highly scalable models for predictive learning • Research and implement novel machine learning and statistical approaches • Work closely with software engineering teams to drive real-time model implementations and new feature creations • Work closely with business owners and operations staff to optimize various business operations • Establish scalable, efficient, automated processes for large scale data analyses, model development, model validation and model implementation • Mentor other scientists and engineers in the use of ML techniques • Innovate with the latest GenAI technology to build highly automated solutions for efficient customer promotions • Design, develop and deploy end-to-end machine learning solutions in the Amazon production environment to delight Amazon customers • Collaborate with cross-functional teams to develop comprehensive ML/statistical models that can scale to millions of customers to multiple countries About the team Brazil Payments is part of the International Emerging Stores Payments team and focuses on supporting the launch of new payment and financial products to our customers in Brazil.
BR, SP, Sao Paulo
Do you feel the challenge and the adrenaline kick when a huge data-set stares you in the face and you know that somewhere inside are hidden very important business insights that can fundamentally alter the way top business leaders think and act? Do you enjoy presenting strong data backed insights to business leaders; insights that can topple their long held beliefs and compel them to change their direction completely? If yes, then you are the one we are looking for. We are looking to invite passionate leaders, with expertise in generate power business insights from very large datasets, on a journey where the primary aim would be to enable needle moving business impacts through statistical analysis. We are looking for leaders who can envision the design and development of analytical infrastructure which can support strategic and tactical decision-making. Those who join this high visibility team would have to navigate through significant ambiguity in defining business problems and converting them to analytical problems. This role requires additional exposure and experience to Machine Learning. Key job responsibilities Use machine learning and analytical techniques to create scalable solutions for business problems • Analyze and extract relevant information from large amounts of Amazon’s historical business data to help automate and optimize key processes • Design, development, evaluate and deploy innovative and highly scalable ml models such as risk scorecards, income models, fraud models for predictive learning in credit risk applications • Research and implement novel machine learning and statistical approaches • Work closely with software engineering teams to drive real-time model implementations and new feature creations • Work closely with business owners and operations staff to optimize various business operations • Establish scalable, efficient, automated processes for large scale data analyses, model development, model validation and model implementation • Mentor other scientists and engineers in the use of ML techniques • Innovate with the latest GenAI technology to build highly automated solutions for efficient customer promotions • Design, develop and deploy end-to-end machine learning solutions in the Amazon production environment to delight Amazon customers • Collaborate with cross-functional teams to develop comprehensive ML/statistical models that can scale to millions of customers to multiple countries Understand the credit risk data and evaluate the best ml model/ solution for dynamic business problems. About the team Brazil Payments is part of the International Emerging Stores Payments team and focuses on supporting the launch of new payment and financial products to our customers in Brazil.