From structured search to learning-to-rank-and-retrieve

Using reinforcement learning improves candidate selection and ranking for search, ad platforms, and recommender systems.

Most modern search applications, ad platforms, and recommender systems share a similar multitier information retrieval (IR) architecture with (at a minimum) a candidate selection or retrieval phase and a candidate ordering or ranking phase. Given a query and a context, the retrieval phase reduces the space of possible candidates from millions, sometimes billions, to (typically) hundreds or less. The ranking phase then fine-tunes the ordering of candidates to be presented to customers. This approach is both flexible and scalable.

Search funnel.png
A typical search funnel, from query understanding to displaying results.

At Amazon Music, we have previously improved our ranking of the top-k candidates by applying learning-to-rank (LTR) models, which learn from customer feedback or actions (clicks, likes, adding to favorites, playback, etc.). We combine input signals from the query, context, customer preferences, and candidate features to train the models.

Related content
Models adapted from information retrieval deal well with noisy GPS input and can leverage map information.

However, these benefits apply only to the candidates selected during the retrieval phase. If the best candidate is not in the candidate set, it doesn’t matter how good our ranking model is; customers will not get what they want.

More recently, we have extended the learning-to-rank approach to include retrieval, in what we are calling learning-to-rank-and-retrieve (LTR&R). Where most existing retrieval models are static (deterministic), learning to retrieve is dynamic and leverages customer feedback.

Consequently, we advocate an approach to learning to retrieve that uses contextual multiarmed bandits, a form of reinforcement learning that optimizes the trade-off between exploring new retrieval strategies and exploiting known ones, in order to minimize “regret”.

In what follows, we review prior approaches to both retrieval and ranking and show how, for all of their success, they still have shortcomings that LTR&R helps address.

Candidate selection strategies

Structured search and query understanding

A common candidate retrieval strategy is full-text search, which indexes free-text documents as bags of words stored in an inverted index using term statistics to generate relevance scores (e.g., the BM25 ranking function). The inverted index maps words to documents containing those words.

Full-text search solves for many search use cases, especially when there is an expectation that the candidates for display (e.g., track titles or artist names) should bear a lexical similarity to the query.

Related content
Applications in product recommendation and natural-language processing demonstrate the approach’s flexibility and ease of use.

We can extend full-text search in a couple of ways. One is to bias the results using some measure of entity quality. For example, we can take the popularity of a music track into account when computing a candidate score such that the more popular of two tracks with identical titles will be more likely to make it into the top page.

We can also extend full-text search by applying it in the context of structured data (often referred to as metadata). For instance, fields in a document might contain entity categories (e.g., product types or topics) or entity attributes (such as brand or color) that a more elaborate scoring function (e.g., Lucene scoring) could take into account.

Structured search (SS) can be effectively combined with query understanding (QU), which maps query tokens to entity categories, attributes, or combinations of the two, later used as retrieval constraints. These methods often use content understanding to extract metadata from free text in order to tag objects or entities with categories and attributes stored as fields, adding structure to the underlying text.

Neural retrieval models

More recently, inspired by advances in representation learning, transformers, and large language models for natural-language processing (NLP), search engineers and scientists have turned their attention to vector search (a.k.a. embedding-based retrieval). Vector search uses deep-learning models to produce dense (e.g., sentence-BERT) as well as sparse (e.g., SPLADE) vector representations, called embeddings, that capture the semantic content of queries, contexts, and entities. These models enable information retrieval through fast k-nearest-neighbor (k-NN) vector similarity searches using exact and approximate nearest-neighbor (ANN) algorithms.

Related content
Thorsten Joachims answers 3 questions about the work that earned him the award.

Vector-and-hybrid (lexical + vector) search yields more relevant results than traditional approaches and runs faster on zero-shot IR models, according to the BEIR benchmark. In recommender systems, customer and session embeddings (as query/context) and entity embeddings are also used to personalize candidates in the retrieval stage. These documents can be further reranked by another LTR neural model in a multistage ranking architecture.

A memory index

Research suggests that users’ actions (e.g., query-click information) are the single most important field for retrieval, serving as a running memory of which entities have worked and which haven’t for a given query/context. In a cold-start scenario, we can even train a model that, when given an input document, generates questions that the document might answer (or, more broadly, queries for which the document might be relevant).

Related content
Amazon scientist’s award-winning paper predates — but later found applications in — the deep-learning revolution.

These predicted questions (or queries) and scores are then appended to the original documents, which are indexed as predicted query-entity (Q2E) scores. Once query-entailed user actions on entities are captured, these computed statistics can replace predicted values, becoming actual Q2E scores that update the memory index used in ranking. As newly encountered queries show up, resulting from hits on other strategies, additional Q2E pairs and corresponding scores will be generated.

Real-world complications

In his article “Throwing needles into haystacks”, Daniel Tunkelang writes,

If you’re interested in a particular song, artist, or genre, your interaction with a search engine should be pretty straightforward. If you can express a simple search intent using words that map directly to structured data, you should reasonably expect the search application to understand what you mean and retrieve results accordingly.

However, as we will show, when building a product that serves millions of customers who express themselves in ways that are particular to their experiences and locales, we cannot reasonably expect queries “to express a search intent using words that map directly to structured data.”

Query processing.png
Processing of the query “tayler love” by a complex QU + SS retrieval system.

Let’s start by unpacking an example. Say we want to process the query “love” in a music search system. Even for a single domain (e.g., music/audio) there are many kinds of entities that could match this query, such as songs, artists, playlists, stations, and even podcasts. For each of these categories there could be hundreds and even thousands of possible candidates matching the keyword “love”. Beyond that, each category has different attributes that can also match the keyword (e.g., “love” maps to the genre “love songs”).

Customers may also expect to see related entities in the search results (e.g., artists related to a song returned). So while in the customer’s mind there is surely a main search intent, expressed via a keyword, there could be many possible mappings or interpretations that should be considered. Each of these has a likelihood of being correct, which would generate series of underlying structured searches, first to identify the possible targeted entities and then to bring along related or derived content.

Related content
Framework improves efficiency, accuracy of applications that search for a handful of solutions in a huge space of candidates.

As we have discovered, the crafting and maintenance of such a system is inherently non-scalable.

There is also the problem of compounding errors due to incorrect query understanding and/or content understanding. Category and attribute assignment to queries and entities, which typically uses a combination of human tagging and ML classification models, could be wrong or even completely missing. Furthermore, assignment values may not be binary. For example, “Taylor Swift” is clearly considered a pop artist, but some of her songs are also categorized as country music, alternative/indie, or indie folk.

Given the centrality of interpretation in selecting candidate results, the ability to learn from interactions with customers is essential to successful retrieval. Search applications based on QU+SS and/or FT search, however, usually use static query plans that cannot incorporate feedback in the retrieval stage.

On the other hand, while deep models show enormous promise, they also require significant investment and seem unlikely to completely replace keyword-based retrieval methods in the foreseeable future.

Learning to retrieve

In a world with infinite resources and no latency constraints, we wouldn’t need a retrieval funnel, and we might prefer to rank all possible candidates. But we don’t live in such a world. The reality is that deciding the right balance between increasing precision, usually by exploiting what we already know works, and increasing recall, by exploring more sources and increasing the number of candidates retrieved, is critical for search, ad platforms, and recommender systems. This is especially true in very dynamic applications such as music search, where context matters and new entities, categories, and attributes get added all the time.

And while it would be terrific if we could identify the single candidate selection strategy that produces an optimal top page for every query/context, in practice this is not achievable. The optimal candidate selection strategy depends on the query/context, but we do not know that dependency a priori. We need to learn to retrieve.

Related content
Two KDD papers demonstrate the power and flexibility of Amazon’s framework for “extreme multilabel ranking”.

One way to try to strike the right explore-exploit trade-off is to implement a multiarmed bandit (MAB) optimization, to learn a policy to select a subset of retrieval strategies (arms) that maximize the sum of stochastic rewards earned through a sequence of searches. That is, the policy should maximize the sum of the likelihoods that the expected results are present in the sets produced by such strategies, as later confirmed by user actions (such as clicking on a link).

The MAB approach uses reinforcement learning (RL) to draw more candidates from strategies that perform well while drawing fewer from underperforming strategies. In particular, for learning-to-retrieve, contextual multiarmed bandit algorithms are ideal, as they are designed to take the query/context features and action features (related to the candidate selection strategy) as input to maximize the reward while keeping healthy rate of exploration to minimize regret.

retrieval ensemble.png
Using reinforcement learning to blend podcast search results from different retrieval strategies.

For example, we expect that embeddings based on language models (i.e., a semantic strategy) will perform better for topic search, while the lexical strategy will be more useful for direct entity search (a.k.a. spearfishing queries).

Query/context features may include query information, such as language, type of query, QU slotting and intent classification, query length, etc.; demographic and profile information about your user; information about the current time, such as day of the week, weekend or not, morning or afternoon, holiday season or not, etc.; and historical (aggregate) data of user behavior, such as what genres of music this user has listened to the most.

Action features may include relevance/similarity scores; historical query-strategy performance and number of results; types of entities retrieved, e.g., newly added, popular, personalized, etc.; and information about the underlying retrieval source, e.g., lexical matching, text/graph embeddings, memory, etc.

The model learns a generalization based on these features and the combination of retrieval strategies that maximizes the reward. Finally, we use the union of results produced by the selected strategies to produce a single candidate list that bubbles up to the ranking layer.

LTR&R.png
Generic learning-to-rank-and-retrieve (LTR&R) architecture.

Summary

In conclusion, using query understanding (when available) and structured search is a good place to start when building search systems. By adding learning-to-rank, you can start to reap the benefits of factoring in customer feedback and improving the system’s quality. However, this is not sufficient to address the hard problems we observe in real-life applications like music search.

As an extension to the common retrieval-and-ranking phases present in the multitier IR architectures used in most search, ads, and recommender systems, we propose a generic learning-to-rank-and-retrieve (LTR&R) system architecture that comprises multiple candidate generators based on different retrieval strategies. Some produce well-known, exploitable results, like those based on our memory index, while others focus more on exploration, producing novel, riskier, or more-unexpected results that can increase the diversity of the feedback and provide counterfactual data.

This feedback cannot be collected by the static (i.e., fully deterministic) retrieval-and-ranking systems used nowadays. We also suggest using ML, and in particular RL, to optimize the selection of the subset of retrieval strategies and the number of candidates drawn from them, to maximize the likelihood of finding the expected result in such sets.

By incorporating customer feedback and using ML for LTR&R we can (1) simplify the search systems and (2) bubble up the best possible candidates for our customers. LTR&R is a promising path to solving both precision-oriented search and broad and ambiguous queries that require more recall and exploration.

Acknowledgments: Chris Chow, Adam Tang, Geetha Aluri, and Boris Lerner

Related content

US, WA, Redmond
At Amazon, we’re inventing on behalf of customers, and with Amazon Leo, we’re redefining what global connectivity looks like. Our mission is to deliver fast, affordable broadband to unserved and underserved communities around the world through a constellation of low Earth orbit (LEO) satellites. Every system we build helps connect people to education, healthcare, opportunity, and each other. As a Data Scientist, you will be responsible for developing advanced analytics and machine learning solutions for user terminals. You will develop predictive models to proactively identify possible user terminal failures in the field. You will work in a collaborative environment with a multi-disciplinary team, including constellation, RF, antenna, silicon, algorithm, and software engineers. Key job responsibilities As a Data Scientist, you will develop analytic tools for a team developing current and future user terminals. Your responsibilities include: • Develop statistical and analytical tool to enable the regression decision from on-orbit and lab measurement of user terminals • Publish documents and create compelling visualizations and presentations to communicate insights to stakeholders • Create and manage datasets for continued pre-training and supervised fine-tuning of LLMs • Develop scalable visualizations for analysis of user terminal performance • Work closely with constellation, RF, antenna, silicon, algorithm, and software engineers to root-cause the failures using data as the primary tool • Drive consensus on metrics and analysis approaches to support product development strategy Export Control Requirement: Due to applicable export control laws and regulations, candidates must be a U.S. citizen or national, U.S. permanent resident (i.e., current Green Card holder), or lawfully admitted into the U.S. as a refugee or granted asylum. A day in the life As a Data Scientist in the LEO Customer Terminal Team, you will work daily with satellite constellation, algorithm, RF, antenna, silicon, hardware, and software teams in a collaborative environment. Your focus will be using data as an intelligence source to enable design decisions for the team. About the team The LEO Customer Terminal team is responsible for developing both outdoor and indoor devices that enable customers to access internet service via the LEO satellite network. We own the entire process from early prototypes through mass production, including requirements documentation, architecture definition, hardware development, algorithm development, and all integration and verification testing.
US, NY, New York
We are seeking an Applied Scientist to lead the development of evaluation frameworks and data collection protocols for robotic capabilities. In this role, you will focus on designing how we measure, stress-test, and improve robot behavior across a wide range of real-world tasks. Your work will play a critical role in shaping how policies are validated and how high-quality datasets are generated to accelerate system performance. You will operate at the intersection of robotics, machine learning, and human-in-the-loop systems, building the infrastructure and methodologies that connect teleoperation, evaluation, and learning. This includes developing evaluation policies, defining task structures, and contributing to operator-facing interfaces that enable scalable and reliable data collection. The ideal candidate is highly experimental, systems-oriented, and comfortable working across software, robotics, and data pipelines, with a strong focus on turning ambiguous capability goals into measurable and actionable evaluation systems. Key job responsibilities - Design and implement evaluation frameworks to measure robot capabilities across structured tasks, edge cases, and real-world scenarios - Develop task definitions, success criteria, and benchmarking methodologies that enable consistent and reproducible evaluation of policies - Create and refine data collection protocols that generate high-quality, task-relevant datasets aligned with model development needs - Build and iterate on teleoperation workflows and operator interfaces to support efficient, reliable, and scalable data collection - Analyze evaluation results and collected data to identify performance gaps, failure modes, and opportunities for targeted data collection - Collaborate with engineering teams to integrate evaluation tooling, logging systems, and data pipelines into the broader robotics stack - Stay current with advances in robotics, evaluation methodologies, and human-in-the-loop learning to continuously improve internal approaches - Lead technical projects from conception through production deployment - Mentor junior scientists and engineers
US, WA, Redmond
Amazon Leo is building a constellation of thousands of low Earth orbit satellites to deliver fast, reliable internet beyond the reach of existing networks. As a Guidance, Navigation & Control engineer, you will design the algorithms, simulations, and onboard autonomy that keep every satellite precisely pointed and stable so the payload can serve customers below, and keep the fleet flying safely. This is satellite GNC with demanding pointing and performance requirements, and you will see your work go from concept to orbit on a constellation that is launching and growing today. Amazon Leo will delight customers with reliable connectivity regardless of where they are. In this role, you will: - Take your GNC algorithms from concept all the way to orbit, and stay close to them through integration, test, and on-orbit operations - Solve hard precise-pointing, payload-cueing, and fleet-autonomy problems against demanding performance requirements - Work across the full lifecycle — design, simulation, test, and flight operations — rather than a narrow slice - Join a small team of some of the top GNC engineers in the industry, building a product people will love to use This position is part of the Satellite Attitude Determination and Control team, where we own the full lifecycle of our work — from algorithm design and flight software, through lab integration, to flying our own satellites on orbit. You will design and analyze the control system and algorithms, support development of our flight hardware and software, help integrate the satellite in our labs, and operate the GNC system in flight as a constellation of satellites flows through the production line into orbit. **Export Control Requirement:** Due to applicable export control laws and regulations, candidates must be a U.S. citizen or national, U.S. permanent resident (i.e., current Green Card holder), or lawfully admitted into the U.S. as a refugee or granted asylum. Key job responsibilities - Design and analyze algorithms for state estimation, attitude determination and control, precise pointing, and payload cueing against demanding performance requirements. - Write the production C++ flight code that runs these algorithms on the satellite. Our GNC engineers own their algorithms all the way into flight software, working alongside software development engineers rather than handing prototypes off to be reimplemented by another team. - Design concepts of operation that balance pointing and payload cueing, momentum management, power, thermal, and communications across all phases of the mission, including off-nominal and contingency scenarios. - Develop momentum management strategies using reaction wheels and magnetic torquers, and help size and lay out the GNC sensor and actuator suite — star trackers, magnetometers, sun sensors, IMUs, and GPS receivers — and the algorithms that consume them. - Develop onboard autonomy, including Fault Detection, Isolation, and Recovery, so the fleet operates safely at scale with minimal intervention. - Develop and validate models and simulations of the satellite and constellation across a range of fidelity levels, including 6-DOF time-domain simulation and Monte Carlo analysis, and run hardware-in-the-loop testing to verify closed-loop performance. - Support component-level environmental testing, functional and performance checkout, and subsystem and satellite integration in our labs. - Analyze fleet telemetry in bulk and build the metrics, dashboards, and tooling that let us monitor and continuously improve pointing performance and payload operations time as the constellation grows. - Operate the GNC system on orbit — reviewing fleet data, supporting maneuvers, and resolving anomalies when on-orbit behavior diverges from the ground model. - Contribute to architecture, design, and code reviews, and document your algorithms, analyses, and results clearly. A day in the life This role spans a diverse set of problems across the spacecraft and network system. You will derive and prototype estimation and control algorithms, turn them into production flight code, and prove them out through 6-DOF and Monte Carlo simulation and hardware-in-the-loop testing in the lab. You will support satellite integration, and when something on orbit does not behave the way the ground model predicted, you will dig into fleet telemetry to find out why and drive the fix. You will own problems end to end and have the focus to go deep on each one. Because GNC sits at the center of safe flight, you will work across the whole program. The payload, power, thermal, and operations teams all depend on GNC, so you will balance their needs against your pointing and momentum budgets. To get your algorithms running reliably on the spacecraft, you will partner closely with avionics, flight software, and our embedded software development engineers. You will help the mechanical teams shape the next generation of satellite hardware, from reaction wheels to star trackers. And as satellites move from design through manufacturing into orbit, you will work alongside systems engineering and Assembly, Integration & Test. The problems are genuinely hard — demanding pointing and performance requirements, a large constellation to keep flying safely, and the chance to invent advanced capabilities that have not been built before. The work is staffed with some of the strongest engineers in the industry, and the constant collaboration across teams makes it a place to keep learning and growing. About the team Our team brings deep experience across many satellite systems and other flight vehicles, with real bench strength in both our mission and the core GNC disciplines. We design, prototype, test, iterate, and learn together, and because GNC is central to safe flight, we tend to drive Concepts of Operation and many of the system-level analyses on the program. We also have a lot of freedom. We trust our engineers to pursue the problems they face in whatever way they find best, to choose their own tools and approaches, and to own the results. If you want the autonomy to solve hard problems your way, and a team of strong engineers to do it with, you will feel at home here.
US, NY, New York
We are seeking an Applied Scientist to lead the development of evaluation frameworks and data collection protocols for robotic capabilities. In this role, you will focus on designing how we measure, stress-test, and improve robot behavior across a wide range of real-world tasks. Your work will play a critical role in shaping how policies are validated and how high-quality datasets are generated to accelerate system performance. You will operate at the intersection of robotics, machine learning, and human-in-the-loop systems, building the infrastructure and methodologies that connect teleoperation, evaluation, and learning. This includes developing evaluation policies, defining task structures, and contributing to operator-facing interfaces that enable scalable and reliable data collection. The ideal candidate is highly experimental, systems-oriented, and comfortable working across software, robotics, and data pipelines, with a strong focus on turning ambiguous capability goals into measurable and actionable evaluation systems. Key job responsibilities - Design and implement evaluation frameworks to measure robot capabilities across structured tasks, edge cases, and real-world scenarios - Develop task definitions, success criteria, and benchmarking methodologies that enable consistent and reproducible evaluation of policies - Create and refine data collection protocols that generate high-quality, task-relevant datasets aligned with model development needs - Build and iterate on teleoperation workflows and operator interfaces to support efficient, reliable, and scalable data collection - Analyze evaluation results and collected data to identify performance gaps, failure modes, and opportunities for targeted data collection - Collaborate with engineering teams to integrate evaluation tooling, logging systems, and data pipelines into the broader robotics stack - Stay current with advances in robotics, evaluation methodologies, and human-in-the-loop learning to continuously improve internal approaches - Lead technical projects from conception through production deployment - Mentor junior scientists and engineers
US, NY, New York
Amazon Advertising is one of Amazon's fastest growing and most profitable businesses, responsible for defining and delivering a collection of advertising products that drive discovery and sales. Our products are strategically important to our businesses driving long term growth. We deliver billions of ad impressions and millions of clicks and break fresh ground in product and technical innovations every day! Advertiser Growth Engine (AGE) team owns and builds services and applications across Amazon World-Wide Advertising that make advertising across multi-marketplaces as easy as flipping on a switch. We are focused on: (1) expanding Amazon Ads advertiser base, and (2) eliminating localization, operational, and marketplace knowledge gap barrier for Advertisers who advertise across multiple marketplaces. Our products and solutions are strategically important to enable our Retail and Marketplace businesses to drive long-term growth globally. We're looking for an experienced Applied Scientist with exceptional technical, analytical, and innovative capabilities to research, design, and create elegant machine learning solutions. The solutions will help our advertisers with multi-media and multi-lingual advertising offerings. You will use ideas from various domains of machine learning, including supervised and unsupervised methods, Deep Neural Networks, Natural Language Processing (NLP), and Computer Vision (CV) to build ML models that localizes multi-media advertising contents, including text, images and videos. You will also identify opportunities to leverage ML beyond localization, including, international expansion and global campaigns. Your work will directly impact our customers in the form of products and services used directly by our advertisers as well as our third-party integrators. As an Applied Scientist on this team, you will: - Build and deliver end-to-end machine learning solutions; build ML models and perform data analysis to deliver scalable solutions to business problems. - Perform hands-on analysis and modeling with enormous data sets to develop insights that increase traffic monetization and merchandise sales without compromising shopper experience. - Work closely with software engineers on detailed requirements to productionize the ML models you build. - Run A/B experiments that affect hundreds of millions of customers, evaluate the impact of your optimizations and communicate your results to various business stakeholders. - Establish scalable, efficient, automated processes for large-scale data analysis, machine-learning model development, model validation and serving. - Research new innovate machine learning approaches. Why you will love this opportunity: Amazon is investing heavily in building a world-class advertising business. This team defines and delivers a collection of advertising products that drive discovery and sales. Our solutions generate billions in revenue and drive long-term growth for Amazon’s Retail and Marketplace businesses. We deliver billions of ad impressions, millions of clicks daily, and break fresh ground to create world-class products. We are a highly motivated, collaborative, and fun-loving team with an entrepreneurial spirit - with a broad mandate to experiment and innovate. Impact and Career Growth: You will invent new experiences and influence customer-facing shopping experiences to help suppliers grow their retail business and the auction dynamics that leverage native advertising; this is your opportunity to work within the fastest-growing businesses across all of Amazon! Define a long-term science vision for our advertising business, driven from our customers' needs, translating that direction into specific plans for research and applied scientists, as well as engineering and product teams. This role combines science leadership, organizational ability, technical strength, product focus, and business understanding. Team video https://youtu.be/zD_6Lzw8raE
IL, Tel Aviv
Are you a scientist interested in pushing the state of the art in Information Retrieval, Large Language Models and Recommendation Systems? Are you interested in innovating on behalf of millions of customers, helping them accomplish their every day goals? Do you wish you had access to large datasets and tremendous computational resources? Do you want to join a team of capable scientist and engineers, building the future of e-commerce? Answer yes to any of these questions, and you will be a great fit for our team at Amazon. Our team is part of Amazon’s Personalization organization, a high-performing group that leverages Amazon’s expertise in machine learning, generative AI, large-scale data systems, and user experience design to deliver the best shopping experiences for our customers. Our team is building next-generation personalization systems powered by Large Language Models. We are tackling novel research challenges to help customers discover products they'll love - at Amazon scale and latency requirements. We are a team uniquely placed within Amazon, to have a direct window of opportunity to influence how customers will think about their shopping journey in the future. As an Applied Science Manager, you will lead a team of scientists working at the frontier of LLM-based personalization. You will set the technical vision, drive the research agenda, and ensure your team delivers production-ready solutions. You will hire, mentor, and develop world-class scientists while fostering a culture of innovation and scientific rigor. You will partner closely with engineering and product teams to translate ambitious research into customer-facing impact, and represent your team's work to senior leadership. Please visit https://www.amazon.science for more information.
US, WA, Seattle
AWS Applied AI Solutions (AAIS) is building toward a future where every business innovates with Amazon AI teammates. To get there, we build AI solutions that improve human capabilities and transform entire business functions. We create end-to-end products that surprise and delight out-of-the-box, making complex things easy and hard things possible, with no cloud experience required. We start with customers who embrace the future and build bridges to meet the rest where they are. We pursue ambitious opportunities with conviction, and we are looking for builders who share that mindset. The Team Join the next science revolution at AWS Life Sciences Applied AI Solutions where you'll work alongside world-class scientists to build AI that transforms how therapeutics are discovered, developed, and brought to patients. We're out to revolutionize how medicines are discovered, developed, and brought to patients powered by a new generation of AI. Our team tackles some of the hardest open problems at the intersection of frontier AI and life sciences. We apply biological foundation models large language models and agentic reasoning systems to life sciences problems then put them into the hands of customers as applications and managed services they can fine-tune tailor and deploy on their own data. The science challenges are deep: how do you design agentic systems that reason correctly over complex biological regulatory and clinical logic? How do you enable customers to tailor foundation models to their proprietary data and get better outputs with less effort? How do you adapt models to reason faithfully in high-stakes scientific and regulatory domains? Today we're focused on two areas. In clinical trials we're building AI that automates and optimizes regulatory and clinical development workflows. In drug design our products (including Amazon Bio Discovery) accelerate discovery by giving bench scientists AI-guided protein engineering and antibody design capabilities. We combine frontier research with production-scale delivery to put breakthrough science into the hands of customers solving humanity's hardest problems. We value scientific rigor encourage publication and support conference participation. If you want to do research that ships this is the team. The Role We are seeking an Applied Scientist to build the models and methods behind our life sciences AI products with a primary focus on clinical trial operations and agentic reasoning. You will design train and evaluate systems that reason over complex clinical and operational logic and ship them into products customers use directly. You will work closely with senior and principal scientists on well-scoped research problems own your results end to end and see your work reach production. This role combines expertise in LLM reasoning and agentic AI with applied impact in life sciences. You will work on how large language models reason plan and act in complex scientific domains while applying domain knowledge to ensure models produce scientifically valid outputs. The problems span multiple fronts: • How do you build LLM-based agentic systems that correctly reason over clinical protocols regulatory standards and complex multi-step operational workflows? • How do you evaluate agent reliability and faithfulness rigorously enough to trust in high-stakes clinical settings? • How do you develop model customization methods (fine-tuning retrieval augmentation domain adaptation) that let customers get strong results from foundation models on their own data? You will focus on clinical trial operations (agentic automation structured reasoning evaluation domain adaptation) with opportunities to contribute across drug discovery (protein engineering antibody design) as the portfolio grows. You will own end-to-end scientific solutions from research through production and your work will directly shape the tools that scientists use daily. Key job responsibilities • Design train fine-tune and evaluate LLM-based agentic systems that reason over clinical protocols regulatory standards and operational workflows • Build rigorous evaluation harnesses and benchmarks to measure agent reliability faithfulness and failure modes in high-stakes domains • Develop model customization methods (fine-tuning RLHF retrieval augmentation domain adaptation) that help customers get better outputs on their own data with less effort • Contribute to graph-based and causal modeling approaches for clinical trial operations • Partner with Life Sciences domain experts product and engineering to translate scientific challenges into shipped capabilities • Own experiments end to end: problem framing implementation evaluation iteration and hand-off to production • Publish at top-tier venues where the work supports it • Contribute to drug discovery efforts (protein engineering antibody design) as opportunities arise A day in the life • Design and run an experiment to validate a new agentic reasoning or fine-tuning method then ship it as a capability customers can use • Diagnose why a model is failing on a new class of inputs and implement a fix to unblock a delivery milestone • Build or extend an evaluation benchmark to measure how faithfully an agent reasons over clinical logic • Meet with domain experts to scope what the next model release needs to do • Review results with a senior scientist sharpen the approach and get it over the finish line • Prototype a new idea that could become the next capability in the product About the team Amazon values diverse experiences. Even if you do not meet all of the preferred qualifications and skills listed in the job description, we encourage candidates to apply. If your career is just starting, hasn't followed a traditional path, or includes alternative experiences, don't let it stop you from applying. Amazon Web Services (AWS) is the world's most comprehensive and broadly adopted cloud platform. We pioneered cloud computing and never stopped innovating — that's why customers from the most successful startups to Global 500 companies trust our robust suite of products and services to power their businesses. We value work-life harmony. Achieving success at work should never come at the expense of sacrifices at home, which is why flexible work hours and arrangements are part of our culture. When we feel supported in the workplace and at home, there's nothing we can't achieve in the cloud. Here at AWS, it's in our nature to learn and be curious. Our employee-led affinity groups foster a culture of inclusion that empower us to be proud of our differences. Ongoing events and learning experiences, including our Conversations on Race and Ethnicity and AmazeCon conferences, inspire us to never stop embracing our uniqueness. We're continuously raising our performance bar as we strive to become Earth's Best Employer. That's why you'll find endless knowledge-sharing, mentorship and other career-advancing resources here to help you develop into a better-rounded professional.
BR, SP, Sao Paulo
Do you feel the challenge and the adrenaline kick when a huge data-set stares you in the face and you know that somewhere inside are hidden very important business insights that can fundamentally alter the way top business leaders think and act? Do you enjoy presenting strong data backed insights to business leaders; insights that can topple their long held beliefs and compel them to change their direction completely? If yes, then you are the one we are looking for. We are looking to invite passionate leaders, with expertise in generate power business insights from very large datasets, on a journey where the primary aim would be to enable needle moving business impacts through statistical analysis. We are looking for leaders who can envision the design and development of analytical infrastructure which can support strategic and tactical decision-making. Those who join this high visibility team would have to navigate through significant ambiguity in defining business problems and converting them to analytical problems. This role requires additional exposure and experience to Machine Learning. Key job responsibilities Use machine learning and analytical techniques to create scalable solutions for business problems • Analyze and extract relevant information from large amounts of Amazon’s historical business data to help automate and optimize key processes • Design, development, evaluate and deploy innovative and highly scalable ml models such as risk scorecards, income models, fraud models for predictive learning in credit risk applications • Research and implement novel machine learning and statistical approaches • Work closely with software engineering teams to drive real-time model implementations and new feature creations • Work closely with business owners and operations staff to optimize various business operations • Establish scalable, efficient, automated processes for large scale data analyses, model development, model validation and model implementation • Mentor other scientists and engineers in the use of ML techniques • Innovate with the latest GenAI technology to build highly automated solutions for efficient customer promotions • Design, develop and deploy end-to-end machine learning solutions in the Amazon production environment to delight Amazon customers • Collaborate with cross-functional teams to develop comprehensive ML/statistical models that can scale to millions of customers to multiple countries Understand the credit risk data and evaluate the best ml model/ solution for dynamic business problems. About the team Brazil Payments is part of the International Emerging Stores Payments team and focuses on supporting the launch of new payment and financial products to our customers in Brazil.
BR, SP, Sao Paulo
Do you feel the challenge and the adrenaline kick when a huge data-set stares you in the face and you know that somewhere inside are hidden very important business insights that can fundamentally alter the way top business leaders think and act? Do you enjoy presenting strong data backed insights to business leaders; insights that can topple their long held beliefs and compel them to change their direction completely? If yes, then you are the one we are looking for. We are looking to invite passionate leaders, with expertise in generate power business insights from very large datasets, on a journey where the primary aim would be to enable needle moving business impacts through statistical analysis. We are looking for leaders who can envision the design and development of analytical infrastructure which can support strategic and tactical decision-making. Those who join this high visibility team would have to navigate through significant ambiguity in defining business problems and converting them to analytical problems. This role requires additional exposure and experience to Machine Learning. Key job responsibilities • Use machine learning and analytical techniques to create scalable solutions for business problems • Analyze and extract relevant information from large amounts of Amazon’s historical business data to help automate and optimize key processes • Design, development, evaluate and deploy innovative and highly scalable models for predictive learning • Research and implement novel machine learning and statistical approaches • Work closely with software engineering teams to drive real-time model implementations and new feature creations • Work closely with business owners and operations staff to optimize various business operations • Establish scalable, efficient, automated processes for large scale data analyses, model development, model validation and model implementation • Mentor other scientists and engineers in the use of ML techniques • Innovate with the latest GenAI technology to build highly automated solutions for efficient customer promotions • Design, develop and deploy end-to-end machine learning solutions in the Amazon production environment to delight Amazon customers • Collaborate with cross-functional teams to develop comprehensive ML/statistical models that can scale to millions of customers to multiple countries About the team Brazil Payments is part of the International Emerging Stores Payments team and focuses on supporting the launch of new payment and financial products to our customers in Brazil.
BR, SP, Sao Paulo
Do you feel the challenge and the adrenaline kick when a huge data-set stares you in the face and you know that somewhere inside are hidden very important business insights that can fundamentally alter the way top business leaders think and act? Do you enjoy presenting strong data backed insights to business leaders; insights that can topple their long held beliefs and compel them to change their direction completely? If yes, then you are the one we are looking for. We are looking to invite passionate leaders, with expertise in generate power business insights from very large datasets, on a journey where the primary aim would be to enable needle moving business impacts through statistical analysis. We are looking for leaders who can envision the design and development of analytical infrastructure which can support strategic and tactical decision-making. Those who join this high visibility team would have to navigate through significant ambiguity in defining business problems and converting them to analytical problems. This role requires additional exposure and experience to Machine Learning. Key job responsibilities Use machine learning and analytical techniques to create scalable solutions for business problems • Analyze and extract relevant information from large amounts of Amazon’s historical business data to help automate and optimize key processes • Design, development, evaluate and deploy innovative and highly scalable ml models such as risk scorecards, income models, fraud models for predictive learning in credit risk applications • Research and implement novel machine learning and statistical approaches • Work closely with software engineering teams to drive real-time model implementations and new feature creations • Work closely with business owners and operations staff to optimize various business operations • Establish scalable, efficient, automated processes for large scale data analyses, model development, model validation and model implementation • Mentor other scientists and engineers in the use of ML techniques • Innovate with the latest GenAI technology to build highly automated solutions for efficient customer promotions • Design, develop and deploy end-to-end machine learning solutions in the Amazon production environment to delight Amazon customers • Collaborate with cross-functional teams to develop comprehensive ML/statistical models that can scale to millions of customers to multiple countries Understand the credit risk data and evaluate the best ml model/ solution for dynamic business problems. About the team Brazil Payments is part of the International Emerging Stores Payments team and focuses on supporting the launch of new payment and financial products to our customers in Brazil.