George Michailidis paper abstract.jpg
Sequential change-point detection in high-dimensional Gaussian graphic models”, published by Hossein Keshavarz, a senior data scientist at relationalAI; George Michailidis; and Yves Atchadé, a professor of statistics at Boston University, touches on the theme of anomaly detection.

George Michailidis: How to identify important changes in online networks

Amazon Scholar discusses the evolution of anomaly detection research.

As the director of the University of Florida Informatics Institute, George Michailidis, who is also an Amazon Scholar on the Supply Chain Optimization Technologies (SCOT) team, leads a diverse community of data scientists with training in engineering, statistics, applied math, and other sciences. He notes that assortment of backgrounds is important in data science.

George Michailidis is the director of the University of Florida Informatics Institute, and an Amazon Scholar on the Supply Chain Optimization Technologies team.
George Michailidis is the director of the University of Florida Informatics Institute, and an Amazon Scholar on the Supply Chain Optimization Technologies team.

“In addition to statistics, there are a number of other disciplines that data scientists need to be aware of, such as programming, algorithms, optimization, and of course, some subject matter expertise because you don't do data science in a vacuum,” he says.

Michailidis was trained in applied mathematics and statistics, with a PhD thesis focused on optimization problems and its applications to statistical problems. His postdoc was in operations research, which introduced him to a different class of problems. “Some of them come about in Amazon’s supply chain, for example, such as problems of how to schedule the jobs on the machine, or how to route the traffic in the network, and so forth.”

For about 17 years, Michailidis was a faculty member at the University of Michigan in statistics with a joint appointment in electrical engineering. “I combined my statistical training with my interest in engineering types of problems.”

Data integration

Since then, his research agenda at the University of Florida has had strong theoretical components, but he remains very interested in practical applications. One of his current interests is data integration, and its many potential uses. For example, when it comes to the study of diseases, there is a wealth of molecular-level data from patients’ samples. At the same time, there is information on the patient's clinical records and demographics.

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“How do you create models to try to identify key drivers, for example, for disease progression by combining all these different data sources,” is one of the questions that motivates Michailidis’ work. With these models, he tries to provide insights both for prognostic or diagnostic purposes, but also for the understanding of the biological mechanisms that lead to that disease.

Another large component of Michailidis’ research relates to a problem known as anomaly detection. “This is an old problem that has been going on for more than 60 years,” he says. To a large extent, it originated in manufacturing, where people were interested in finding defects in the manufacturing process and fixing them. As the technology evolved, similar questions have been arising in many other fields.

This is broadly the theme of a paper published by Michailidis and his colleagues Hossein Keshavarz, a senior data scientist at relationalAI, and Yves Atchadé, a professor of statistics at Boston University, entitled “Sequential change-point detection in high-dimensional Gaussian graphic models.”

Michailidis notes that, as manufacturing processes became more complex, it became necessary to monitor many more metrics.

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“A typical example of this complexity is semiconductor manufacturing, where you have to monitor hundreds of little things,” he says.

In more modern applications, the next step is to monitor networks.

“You’re not only monitoring a lot of things. Now these things are interconnected and you're trying to understand how this network, as an object, changes its structure at some point in time,” Michailidis explains. “And you're doing that in an online fashion because this process keeps going. You keep observing the network and you're trying to identify changes as quickly as possible.”

In addition to developing a technique to detect changes, researchers also must establish that their technique is sensitive enough for certain types of changes and determine whether it detects them quickly enough. This is the challenge, in the online realm, that Michailidis and his colleagues attempt to address in their paper. The paper introduces “introduces a novel scalable online algorithm for detecting an unknown number of abrupt changes”.

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In the paper, the authors present an application on stock market data, where the network is made of movements of stocks. “We showed how the network changes, for example, during the great financial crisis of 2008, and how the stock market got affected by the European debt crisis in 2012 and so forth.” Michailidis notes that these techniques are especially suited for problems where there are dependencies between observable elements without knowledge of the nature of those dependencies.

“With stocks, whether they are moving together or in different directions, these movements —or lack of movement — is what gives rise to the network structure. And that’s what we are capturing with these graphical models,” he says.

Within the SCOT organization, Michailidis says he has the opportunity to tackle challenging problems at an unprecedented scale. “The problems are much more complex because they're not as clear cut as they are in academia.” In this interview, he discusses his research on anomaly detection and its potential applications.

  1. Q. 

    Your paper mentions high dimensional piecewise sparse graphical models. What does that entail and what are some applications?

    A. 

    The graphical model is a particular statistical model that tries to capture statistical dependencies between the things that are measured on the nodes. In the stock market example, you're looking at the rate of return of a stock. This is the measurement that you have on every node over time and you're trying to understand, for example, whether the return of one technology stock is correlated with the return of some other technology stock. So that's what the graphical model is trying to capture — the statistical dependencies.

    The next step is what we mean by high dimensional. Essentially, it means that the number of nodes, or variables, in your network becomes very large compared to how many observations you have. You may have a short observation period, but with a high number of nodes. What we call high-dimensional statistics became a big field of study 15 to 20 years ago, with a lot of applications. The reason is that, in more classical statistics, we always made the assumption that the sample size in our observations is much larger than the number of variables. In the high-dimensional regime, the relationship flips and you have many more variables than observations and that poses a whole bunch of technical challenges, to the point where you can’t even solve the problem.

    So, you need some additional assumptions, and that's where another important term comes in: sparse. This means that this network doesn't have too many connections. If it was very well connected, then we would not be able to solve the problem for technical reasons, because you would not have enough data. So, you make the assumption that these networks are not too connected to compensate for how much data you have.

    And the last term we need to understand is piecewise. By piecewise, we mean that, for this period, the network structure stays the same, and then changes abruptly to some other structure. It's not a gradual change — although this may be happening in reality. It heavily depends on the underlying application. It may either be a simplifying assumption in order to do the analysis or, in many cases, that's exactly what happens.

    In the neuroscience example, if the subject sits in the scanner without moving, and then you tell them — “raise your hand or read this sentence” — there is an abrupt change because there is a new task after a resting state. This is also possible in the stock market, where new information may create these abrupt changes.

    In many applications, there is really an abrupt change and this is the proper setting to use. In some other cases, changes may be a little bit more gradual. But we can still look at them as abrupt changes because it becomes a good working hypothesis and simplifies things. A lot of these techniques that people develop are good working models, and not exactly what's going on, that's fairly standard in a lot of scientific fields. And that explains the high dimensional piecewise sparse graphical model. That's where all the pieces come together.

  2. Q. 

    Why is it important to be able to detect these abrupt changes in an online setting?

    A. 

    Because you keep collecting the data, and you would like to identify these changes as things evolve. You could solve the same problem, with the same high dimensional sparse piecewise graphical model, in an offline manner. In that case, the difference is that you have already collected these data and would like to explore them in a retrospective manner to see if you can find these types of changes. That's also a problem of interest.

    The reason that in this article we focus on online detection is that we have already done work on the offline version, so it was natural to start exploring what is different in an online setting. And it's much, much more challenging, because you don't know the future and you keep getting new information, and you're trying to detect these changes quickly. Online problems in machine learning and other areas are more challenging than offline problems, as a general rule. So, this is for me a natural evolution, since I’ve already used these sparse graphical models in an offline setting.

  3. Q. 

    What does the paper demonstrate and how is it applicable to Amazon?

    A. 

    The paper does demonstrate that it is possible to detect these changes online, so it’s a positive message. And it also shows a caveat. If, for example, the changes in this connectivity pattern were concentrated on only one node, then we could not detect them with the current technology. Because that's a very localized change, it only involves a very tiny part of the network. And our technique would only be able to detect them by waiting for a very long time. From an applications perspective, that makes it uninteresting. That tells you the limitations, which are important in some settings. We have done most of the work, but we found out that we were missing something. So, we need to go and develop a little bit more.

    The results could be applicable to Amazon because these graphical models come up a lot. So far, we have used techniques where we haven't taken the connections into account, we have just looked simply at what is going on in the time series, let's say, of a single node and whether that changes. Obviously, given the fact that Amazon operates in a highly volatile environment, changes are important. In the longer term, given the fact that the team has done work with graphical models, it may be interesting to utilize some of these techniques. The potential is there.

    In general, anomaly detection work to date across many disciplines (statistics, signal processing, machine learning, econometrics) has largely focused on parametric models, where with some effort the theoretical properties of anomaly detection procedures can be elucidated analytically and then validated through simulations. The analytical work provides deeper insights into the performance of these anomaly detection procedures and their limitations, and when they do not perform well. With all the advances in deep learning models, they become prime tools to use in anomaly detection problems.

    However, the challenge then becomes, to understand the performance limits of such models, beyond relying on numerical work. Such advances may take some time, but once the community makes progress, much more powerful procedures will be available to the practitioners.

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Are you driven by the challenge of solving complex problems that directly impact the safety and well-being of millions of Amazon Associates worldwide? Do you want to push the boundaries of AI to build innovative solutions that make workplaces safer and more efficient? If so, we invite you to join our WHS DataTech team as an Applied Scientist and take your career to the next level! At WHS DataTech, we leverage Large Language Models (LLMs), Computer Vision, and AI-driven innovations to develop industry-leading solutions that proactively enhance workplace safety. Our work spans real-time risk assessment, predictive analytics, and AI-powered insights, all aimed at creating a safer work environment at scale. As an Applied Scientist specializing in LLMs and Computer Vision, you will play a pivotal role in shaping our next-generation safety solutions. You’ll be at the forefront of innovation, designing and implementing AI-powered features that redefine workplace safety. Your work will drive strategic decisions, optimize system architecture, and influence best practices, ensuring our technology remains industry-leading. Key job responsibilities - Apply LLM model to analyze complex unstructured datasets and extract meaningful insights. - Collaborate with software engineers to implement and deploy machine learning (LLM or CV) solutions. - Conduct experiments and evaluate model performance, iterating and improving as needed. - Stay up-to-date with the latest advancements in machine learning and related fields. - Collaborate with cross-functional teams to understand business needs and identify areas for application of machine learning. - Present findings and recommendations to stakeholders and contribute to the overall research and development strategy. A day in the life Amazon offers a full range of benefits that support you and eligible family members, including domestic partners and their children. Benefits can vary by location, the number of regularly scheduled hours you work, length of employment, and job status such as seasonal or temporary employment. The benefits that generally apply to regular, full-time employees include: 1. Medical, Dental, and Vision Coverage 2. Maternity and Parental Leave Options 3. Paid Time Off (PTO) 4. 401(k) Plan If you are not sure that every qualification on the list above describes you exactly, we'd still love to hear from you! At Amazon, we value people with unique backgrounds, experiences, and skillsets. If you’re passionate about this role and want to make an impact on a global scale, please apply! About the team WHS DataTech is a multidisciplinary team of scientists and engineers dedicated to building AI-powered solutions that improve workplace safety across Amazon. We work at the intersection of large-scale data, advanced machine learning, and computer vision, delivering innovations that enhance decision-making, streamline operations, and protect millions of associates worldwide. Our collaborative culture emphasizes scientific rigor, engineering excellence, and a strong mission focus on creating safer, more efficient workplaces.
US, CA, Pasadena
The Amazon Center for Quantum Computing (CQC) is a multi-disciplinary team of scientists, engineers, and technicians, on a mission to develop a fault-tolerant quantum computer. We are looking to hire an Instrument Control Engineer to join our growing software team. You will work closely with our experimental physics and control hardware development teams to enable their work characterizing, calibrating, and operating novel quantum devices. The ideal candidate should be able to translate high-level science requirements into software implementations (e.g. Python APIs/frameworks, compiler passes, embedded SW, instrument drivers) that are performant, scalable, and intuitive. This requires someone who (1) has a strong desire to work within a team of scientists and engineers, and (2) demonstrates ownership in initiating and driving projects to completion. This role has a particular emphasis on working directly with our control hardware designers and vendors to develop instrument software for test and measurement. Inclusive Team Culture Here at Amazon, it’s in our nature to learn and be curious. Our employee-led affinity groups foster a culture of inclusion that empower us to be proud of our differences. Ongoing events and learning experiences, including our Conversations on Race and Ethnicity (CORE) and AmazeCon conferences, inspire us to never stop embracing our uniqueness. Diverse Experiences Amazon values diverse experiences. Even if you do not meet all of the qualifications and skills listed in the job description, we encourage candidates to apply. If your career is just starting, hasn’t followed a traditional path, or includes alternative experiences, don’t let it stop you from applying. Mentorship & Career Growth We’re continuously raising our performance bar as we strive to become Earth’s Best Employer. That’s why you’ll find endless knowledge-sharing, mentorship and other career-advancing resources here to help you develop into a better-rounded professional. Work/Life Balance We value work-life harmony. Achieving success at work should never come at the expense of sacrifices at home, which is why we strive for flexibility as part of our working culture. When we feel supported in the workplace and at home, there’s nothing we can’t achieve in the cloud. Export Control Requirement Due to applicable export control laws and regulations, candidates must be either a U.S. citizen or national, U.S. permanent resident (i.e., current Green Card holder), or lawfully admitted into the U.S. as a refugee or granted asylum, or be able to obtain a US export license. If you are unsure if you meet these requirements, please apply and Amazon will review your application for eligibility. Key job responsibilities - Work with control hardware developers, as a “subject matter expert” on the software interfaces around our control hardware - Collaborate with external control hardware vendors to understand and refine integration strategies - Implement instrument drivers and control logic in Python and/or a low-level languages, including C++ or Rust - Contribute to our compiler backend to enable the efficient execution of OpenQASM-based experiments on our next-generation control hardware - Benchmark system performance and help define key performance metrics - Ensure new features are successfully integrated into our Python-based experimental software stack - Partner with scientists to actively contribute to the codebase through mentorship and documentation We are looking for candidates with strong engineering principles, a bias for action, superior problem-solving, and excellent communication skills. Working effectively within a team environment is essential. As an Instrument Control Engineer embedded in a broader science organization, you will have the opportunity to work on new ideas and stay abreast of the field of experimental quantum computation. A day in the life Your time will be spent on projects that extend functional capabilities or performance of our internal research software stack. This requires working backwards from the needs of science staff in the context of our larger experimental roadmap. You will translate science and software requirements into design proposals balancing implementation complexity against time-to-delivery. Once a design proposal has been reviewed and accepted, you’ll drive implementation and coordinate with internal stakeholders to ensure a smooth roll out. Because many high-level experimental goals have cross-cutting requirements, you’ll often work closely with other engineers or scientists or on the team. About the team You will be joining the Software group within the Amazon Center of Quantum Computing. Our team is comprised of scientists and software engineers who are building scalable software that enables quantum computing technologies.