Alessandro Achille, a senior applied scientist at Amazon Web Services, is seen standing outside at night with a display of colored lights in the background
Alessandro Achille, a senior applied scientist at Amazon Web Services, is tackling fundamental challenges that are shaping the future of computer vision and large generative-AI models.

“I don't remember a time in my life when I wasn't interested in science"

From the urgent challenge of "machine unlearning" to overcoming the problem of critical learning periods in deep neural networks, Alessandro Achille is tackling fundamental issues on behalf of Amazon customers.

It was on a “hunting trip” to Italy in 2015 that computer vision pioneer Stefano Soatto first came across Alessandro Achille. More accurately, it was a mind-hunting trip, to the prestigious Scuola Normale Superiore in Pisa. The university was founded by Napoleon, and its alumni include Nobel-Prize-winning physicists Enrico Fermi and Carlo Rubbia and Field-Medal-winning mathematician Alessio Figalli. “It puts students through a grueling selection and training process,” says Soatto, “so those who survive are usually highly capable — and rugged.”

It was a successful trip that evolved into a powerful research partnership. Today, Achille is working as a senior applied scientist at Amazon Web Services' (AWS') AI Lab, on the California Institute of Technology (Caltech) campus, tackling fundamental challenges that are shaping the future of computer vision (CV) and large generative-AI models.

But back in 2015, Achille was immersed in a master’s in pure mathematics, “spiced up”, as he puts it, with algebraic topology.

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“I don't remember a time in my life when I wasn't interested in science,” he says. Achille was particularly interested in the foundations of mathematics. “I focused on logic, because I’ve always had this nagging problem at the back of my mind of exactly why things are the way they are in mathematics.”

Achille’s first taste of computer vision arose when he and his peers decided to augment an annual school tradition: a 24-hour foosball tournament between mathematicians and physicists. Besides a sport competition, the event had become a showcase of the students’ engineering capabilities. That year, after adding live streaming and a fully automated scorekeeping system, the students thought it was time to add real-time tracking of the ball.

“It’s just a white blob moving on a green background. How hard could it be?” says Achille. The short answer is, harder than they thought. So Achille took a class that would teach him more — a choice that would eventually lead to an invitation from Soatto to join him at the University of California, Los Angeles, for a PhD in computer vision.

“In Italian education, it sometimes feels like there is a hierarchy,” says Achille. “The more abstract you are, the better you are doing!” So why the departure from pure mathematics? In the end, says Soatto, “Alessandro’s work became so abstract he couldn’t see a path to impact. That’s very frustrating for a really smart person who wants to make a difference in the world.”

Deep learning takes off

Achille’s PhD coincided with the rise of deep learning (DL), which would become a game-changing technology in machine learning and computer vision. “At the time, we didn't know if it was anything more than just a new, slightly more powerful tool. We didn’t know if DL had the power of abstraction, reasoning, and so on,” says Achille.

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The power of deep learning was becoming clear, though. During an internship in 2017, Achille worked on a computer vision model that could learn a representation of a dynamic scene — a 3-D shape that was moving, changing color, changing orientation, and so on.

The idea was to capture and isolate the semantic components of the scene — shape, size, color, or angle of rotation — rather than capturing the totality of the scene’s characteristics. Humans do this disentangling naturally. That’s how you would understand the sight of a blue banana, even if you had never seen one before: “banana” and “blue” are separate semantic components.

While Achille enjoyed the project and appreciated its importance, he was struck by the artificiality of the setting. “I was not working backwards from a use case,” he says. Shortly after, Achille became an intern at the AWS AI Lab that had just been established at the Caltech campus, where he was immediately given a real-world challenge to solve on a newly launched product called Custom Label.

Real-world problems

At the time, Custom Label allowed Amazon customers to access CV models that could be trained to identify, say, their company’s products in images — a particular faucet, for example. The models could also be trained to perform tasks like identifying something in a video or analyzing a satellite image.

AWS researchers realized it was impractical to expect a single model to accurately deal with such a range of esoteric image possibilities. A better approach was to pretrain many expert models on different imagery domains and then select the most appropriate one to fine-tune on the customer’s data. The problem for AWS was, how could it efficiently discover which of 100 or more pretrained CV models would perform best?

Alessandro Achille: The information in a deep neural network

During his research in machine learning, Achille became passionate about information theory — a mathematical framework for quantifying, storing, and communicating information. So he used that approach on this so-called model selection problem. “For a hammer, everything looks like a nail,” he laughs.

The problem is how to measure the “distance" between two learning tasks — the task a given AWS model has been pretrained on and the novel customer task. In other words, how much additional information is required by the pretrained model to produce a good performance on the customer task? The less additional information required, the better.

Achille was impressed by the task because it was an important customer issue with a fundamental mathematical problem behind it. “We formulated an algorithm to compute this efficiently, so we could easily select the expert model best suited to solving the customer’s task,” says Achille. “It was the first solution to this problem.”

Achille found Amazon’s applied approach to be a compelling way to work, and when Soatto established the AWS AI Labs, Achille was happy to join him there.

“One of the beauties of being at Amazon is that we’re tackling some of the world's most challenging emerging problems,” says Soatto. “Because when AWS customers have difficult problems to address, they come to us. From a scientific perspective, this is a goldmine.”

Machine unlearning

Achille is currently staking out a vein of research gold in a critical new area of artificial intelligence (AI): AI model disgorgement, more popularly known as "machine unlearning". It is critical in any implementation of machine learning models that the data used to train the model are used responsibly, in a privacy-preserving manner, and in accordance with the appropriate regulations and intellectual-property rights.

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Modern ML models have become very large and complex, requiring a great deal of data and computational resources to train. But what if, once a model is trained, the contributor of some of those training data decides, or is obligated by law, to withdraw the data from the model? Or what if some of the training data is discovered to be biased? Retraining a large model afresh, with some data withheld, may be impractical, particularly if the requirement for such changes becomes commonplace in the shifting legal landscape.

The next level

In 2019 that Soatto, Achille, and Achille's fellow UCLA PhD student Aditya Golatkar published a paper entitled “Eternal Sunshine of the Spotless Net: Selective Forgetting in Deep Networks”; the paper established a novel method for removing the effects of a subset of a deep neural network's training data, without requiring retraining.

Eternal sunshine of the spotless net: Selective forgetting in deep networks

“I was happy to see interest in ‘selective forgetting’ explode after we published this paper,” says Achille. “Model disgorgement is a fascinating problem, and not only because it's very important for AWS customers. It also demands that we understand everything about a model’s neural network. We need to understand where information is held in a model’s weights, how it is encoded, how it is measured.”

It is in this fundamental work that Achille took the field to “the next level”, says Soatto. And this year, Achille and Soatto, on a team also featuring Amazon Scholar Michael Kearns, coauthor of the book The Ethical Algorithm, led the field by introducing a taxonomy of possible disgorgement methods applicable to modern ML systems.

The paper also describes ways to train future models so that they are amenable to subsequent disgorgement.

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“It is better for models to learn in a compartmentalized fashion, so in the event that some data is found to be problematic, everything that touched those data gets thrown away, while the rest of the model survives without having to retrain it from scratch,” says Soatto.

This work has been particularly satisfying, says Achille, as it obliged computer scientists, mathematicians, lawyers, and policymakers to work closely together to solve a pressing modern problem.

Critical learning periods

The breadth of Achille’s interests is formidable. His other prominent research includes work on “critical learning periods” in the training of deep networks. The work arose through serendipity, after a friend studying for a medical exam on the profound effect of critical learning periods in humans jokingly asked Achille if his networks also had them. Interest piqued, Achille explored the idea, and found some striking similarities.

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For example, take infantile strabismus, a condition in which a person's eyes do not align properly from birth or early infancy. If not treated early, the condition can cause amblyopia, whereby the brain learns to trust the properly working eye and to ignore the visual input from the misaligned eye, to avoid double vision.

This one-sided competition between the two eyes (data sources) leads to worsening vision in the misaligned eye and of course the loss of stereo vision, which is important for depth perception. Amblyopia is difficult to reverse if left untreated into adulthood. But treating the eyes early, enabling them to work together optimally, makes for a robust vision system.

Similarly, in the early training of multimodal deep neural networks, one type of data may become favored over another, simply through expediency. For example, in a visual-question-answering model, which is trained on images and captions, the easy-to-use textual information may outcompete visual information, leading to models that are effectively blind to visual information. Achille and his colleagues suggest that when a DL model takes such shortcuts, it has irreversible effects on the subsequent performance of the model, making it less flexible — and therefore less useful — when fine-tuned on novel data.

Off the charts

Having explored the causes of critical learning periods in deep networks, the team offered new techniques for stabilizing the early learning dynamics in model training and showed how this approach can actually prevent critical periods in deep networks. The practical benefits of this research aside, Achille enjoys exploring the parallelisms of artificial and biological systems.

“Look, we can all recognize that the actual hardware of a network and a brain are completely different, but can we also recognize that they are both systems that are trying to process information efficiently and trying to learn something?” he asks. Are there some fundamental dynamics of learning, and how it relates to the acquisition of information, that are shared between synthetic and biological systems? Watch this space.

Looking back on the eight years since his hunting trip to Pisa, Soatto considers what he most appreciates about his Amazon colleague.

“First, the brilliance of the way Alessandro frames problems: he thinks very abstractly, yet he is also a hacker who thinks broadly, all the way from mathematics to neuroscience, from art to engineering — this is very rare. Second, his curiosity, which is absolutely off the charts.”

For Achille’s part, when asked if he prefers tackling the challenges that arise from AWS products or working on fundamental science problems, he demurs. “I don’t need to split my time between product and fundamental research. For me, it ends up being the same thing.”

Indeed, one of Amazon’s most abstract thinkers has found a path to true impact.

Research areas

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Are you interested in a unique opportunity to advance the accuracy and efficiency of Artificial General Intelligence (AGI) systems? If so, you're at the right place! We are the AGI Autonomy organization, and we are looking for a driven and talented Member of Technical Staff to join us to build state-of-the art agents. Our lab is a small, talent-dense team with the resources and scale of Amazon. Each team in the lab has the autonomy to move fast and the long-term commitment to pursue high-risk, high-payoff research. We’re entering an exciting new era where agents can redefine what AI makes possible. We’d love for you to join our lab and build it from the ground up! Key job responsibilities * Design and implement a modern, fast, and ergonomic development environment for AI researchers, eliminating current pain points in build times, testing workflows, and iteration speed * Build and manage CI/CD pipelines (CodePipeline, Jenkins, etc.) that support large-scale AI research workflows, including pipelines capable of orchestrating thousands of simultaneous agentic experiments * Develop tooling that bridges local development environments with remote supercomputing resources, enabling researchers to seamlessly leverage massive compute from their IDEs * Manage and optimize code repository infrastructure (GitLab, Phabricator, or similar) to support collaborative research at scale * Implement release management processes and automation to ensure reliable, repeatable deployments of research code and models * Optimize container build systems for GPU workloads, ensuring fast iteration cycles and efficient resource utilization * Work directly with researchers to understand workflow pain points and translate them into infrastructure improvements * Build monitoring and observability into development tooling to identify bottlenecks and continuously improve developer experience * Design and maintain build systems optimized for ML frameworks, CUDA code, and distributed training workloads About the team The team is shaping developer experience from the ground up. Building tools that enable researchers to move at the speed of thought: IDEs that seamlessly shell out to supercomputers, CI/CD pipelines that orchestrate thousands of agentic commands simultaneously, and build systems optimized for GPU-accelerated workflows. Your infrastructure will be the foundation that enables the next generation of AI research, directly contributing to our mission of building the most capable agents in the world.
US, CA, San Francisco
Are you interested in a unique opportunity to advance the accuracy and efficiency of Artificial General Intelligence (AGI) systems? If so, you're at the right place! We are the AGI Autonomy organization, and we are looking for a driven and talented Member of Technical Staff to join us to build state-of-the art agents. Our lab is a small, talent-dense team with the resources and scale of Amazon. Each team in the lab has the autonomy to move fast and the long-term commitment to pursue high-risk, high-payoff research. We’re entering an exciting new era where agents can redefine what AI makes possible. We’d love for you to join our lab and build it from the ground up! Key job responsibilities * Design, build, and maintain the compute platform that powers all AI research at the SF AI Lab, managing large-scale GPU pools and ensuring optimal resource utilization * Partner directly with research scientists to understand experimental requirements and develop infrastructure solutions that accelerate research velocity * Implement and maintain robust security controls and hardening measures while enabling researcher productivity and flexibility * Modernize and scale existing infrastructure by converting manual deployments into reproducible Infrastructure as Code using AWS CDK * Optimize system performance across multiple GPU architectures, becoming an expert in extracting maximum computational efficiency * Design and implement monitoring, orchestration, and automation solutions for GPU workloads at scale * Ensure infrastructure is compliant with Amazon security standards while creatively solving for research-specific requirements * Collaborate with AWS teams to leverage and influence cloud services that support AI workloads * Build distributed systems infrastructure, including Kubernetes-based orchestration, to support multi-tenant research environments * Serve as the bridge between traditional systems engineering and ML infrastructure, bringing enterprise-grade reliability to research computing About the team This role is part of the foundational infrastructure team at the SF AI Lab, responsible for the platform that enables all research across the organization. Our team serves as the critical link between Amazon's enterprise infrastructure and the Lab's research needs. We are experts in performance optimization, systems architecture, and creative problem-solving—finding ways to push the boundaries of what's possible while maintaining security and reliability standards. We work closely with research scientists, understanding their experimental needs and translating them into robust, scalable infrastructure solutions. Our team has deep expertise in ML framework internals and GPU optimization, but we're also pragmatic systems engineers who build traditional infrastructure with enterprise-grade quality. We value engineers who can balance research velocity with operational excellence, who bring curiosity about ML while maintaining strong fundamentals in systems engineering. This is a small, high-impact team where your work directly enables breakthrough AI research. You'll have the opportunity to work with some of the most advanced AI infrastructure in the world while building the skills that define the future of ML systems engineering.
US, NY, New York
About Sponsored Products and Brands The Sponsored Products and Brands team at Amazon Ads is re-imagining the advertising landscape through industry leading generative AI technologies, revolutionizing how millions of customers discover products and engage with brands across Amazon.com and beyond. We are at the forefront of re-inventing advertising experiences, bridging human creativity with artificial intelligence to transform every aspect of the advertising lifecycle from ad creation and optimization to performance analysis and customer insights. We are a passionate group of innovators dedicated to developing responsible and intelligent AI technologies that balance the needs of advertisers, enhance the shopping experience, and strengthen the marketplace. If you're energized by solving complex challenges and pushing the boundaries of what's possible with AI, join us in shaping the future of advertising. About our team The Search Ranking and Interleaving (R&I) team within Sponsored Products and Brands is responsible for determining which ads to show and the quality of ads shown on the search page (e.g., relevance, personalized and contextualized ranking to improve shopper experience, where to place them, and how many ads to show on the search page. This helps shoppers discover new products while helping advertisers put their products in front of the right customers, aligning shoppers’, advertisers’, and Amazon’s interests. To do this, we apply a broad range of GenAI and ML techniques to continuously explore, learn, and optimize the ranking and allocation of ads on the search page. We are an interdisciplinary team with a focus on improving the SP experience in search by gaining a deep understanding of shopper pain points and developing new innovative solutions to address them. A day in the life As an Applied Scientist on this team, you will identify big opportunities for the team to make a direct impact on customers and the search experience. You will work closely with with search and retail partner teams, software engineers and product managers to build scalable real-time GenAI and ML solutions. You will have the opportunity to design, run, and analyze A/B experiments that improve the experience of millions of Amazon shoppers while driving quantifiable revenue impact while broadening your technical skillset. Key job responsibilities - Solve challenging science and business problems that balance the interests of advertisers, shoppers, and Amazon. - Drive end-to-end GenAI & Machine Learning projects that have a high degree of ambiguity, scale, complexity. - Develop real-time machine learning algorithms to allocate billions of ads per day in advertising auctions. - Develop efficient algorithms for multi-objective optimization using deep learning methods to find operating points for the ad marketplace then evolve them - Research new and innovative machine learning approaches. - Recruit Scientists to the team and provide mentorship.