Card-Imbens 16x9.jpg
David Card (left), an Amazon Scholar, a professor of economics at the University of California, Berkeley, and the outgoing president of the AEA, and Guido Imbens (right), an academic research consultant at Amazon and a professor at the Stanford Graduate School of Business.

A conversation with economics Nobelists

Amazon Scholar David Card and academic research consultant Guido Imbens on the past and future of empirical economics.

The annual meeting of the American Economic Association (AEA) took place Jan. 7 - 9, and as it approached, Amazon Science had the chance to interview two of the three recipients of the 2021 Nobel Prize in economics — who also happen to be Amazon-affiliated economists.

David Card, an Amazon Scholar, a professor of economics at the University of California, Berkeley, and the outgoing president of the AEA, won half the prize “for his empirical contributions to labor economics”.

Guido Imbens, an academic research consultant at Amazon and a professor at the Stanford Graduate School of Business, shared the other half of the prize with MIT’s Josh Angrist for “methodological contributions to the analysis of causal relationships”.

Amazon Science: The empirical approach to economics has been recognized by the Nobel Prize committee several times in the last few years, but it wasn't always as popular as it is today. I'm curious how you both first became interested in empirical approaches to economics.

David Card: The heroes of economics for many, many decades were the theorists, and in the postwar era especially, there was a recognition that economic modeling was underdeveloped — the math was underdeveloped — and there was a need to formalize things and understand better what the models really delivered.

People started to realize that we had the data to better look at real labor market phenomena and possibly make economics something different than just a kind of a branch of philosophy.
David Card

That need really proceeded through the ’60s, and Arrow and Debreu were these famous mathematical economists who developed some very elegant theoretical models of how the market works in an idealized economy.

What happened in my time was people started to realize that we had the data to better look at real labor market phenomena and possibly make economics something different than just a kind of a branch of philosophy. Arrow-Debreu is basically mathematical philosophy.

Guido Imbens: I came from a very different tradition. I grew up in the Netherlands, and there was a strong tradition of econometrics started by people like Tinbergen. Tinbergen had been very broad — he did econometrics, but he also did empirical work and was very heavily involved in policy analysis. But over time, the program he had started was becoming much more focused on technical econometrics.

So as an undergraduate, we didn't really do any empirical work. We really just did a lot of mathematical statistics and some operations research and some economic theory. My thesis was a theoretical econometrics study.

When I presented that at Harvard, Josh Angrist wasn't really all that impressed with it, and he actually opposed the department hiring me there because he thought the paper was boring. And he was probably right! But luckily, the more senior people there at the time thought I was at least somewhat promising. And so I got hired at Harvard. But then it was really Josh and Larry Katz, one of the labor economists there, who got me interested in going to the labor seminar and got me exposed to the modern empirical work.

The context Josh and I started talking in really was this paper that I think came up in all three of the Nobel lectures, this paper by Ed Leamer, “Let's Take the Con Out of Econometrics”, where Leamer says, “Hardly anyone takes data analysis seriously. Or perhaps more accurately, hardly anyone takes anyone else’s data analysis seriously.”

And I think Leamer was right: people did these very elaborate things, and it was all showing off complicated technical things, but it wasn't really very credible. In fact, Leamer presented a lecture based on that work at Harvard. And I remember Josh getting up at some point and saying, “Well, you talk about all this old stuff, but look at the work Card does. Look at the work Krueger does. Look at the work I do. It's very different.”

And that felt right to me. It felt that the work was qualitatively very different from the work that Ed Leamer was describing and that he was complaining about.

AS: So that's when you first became aware of Professor Card’s work. Professor Card, when did you first become aware of Professor Imbens’s work?

Card: One of his early papers was pretty interesting. He was trying to combine data from micro survey evidence with benchmark numbers that you would get from a population, and it's actually a version of a kind of a problem that arises at Amazon all the time, which is, we've got noisy estimates of something, and we've got probably reliable estimates of some other aggregates, and there's often ways to try and combine those. I saw that and I thought that was very interesting.

Then there’s the problem that Josh and Guido worked on that was most impactful and that was cited by the Nobel Prize committee. I had worked on an experiment, a real experiment [as opposed to a natural experiment], in welfare analysis in Canada, and it was providing an economic incentive to try and get single mothers off of welfare and into work. And we noticed that the group of mothers who complied or followed on with the experiment was reasonable size, but it wasn't 100%.

We did some analysis of it trying to characterize them. Around the same time, I became aware of Imbens’s and Angrist’s paper, which basically formalized that a lot better and described what exactly was going on with this group. That framework just instantly took off, and everyone within a few years was thinking about problems that way.

This morning I was talking to another Amazon person about a problem. It was a difference analysis. I was saying we should try and characterize the compliers for this difference intervention. So it's exactly this problem.

The Nobel committee’s press release for Card, Imbens, and Angrist’s prize announcement emphasizes their use of natural experiments, which it defines as “situations in which chance events or policy changes result in groups of people being treated differently, in a way that resembles clinical trials in medicine.” A seminal instance of this was Card’s 1993 paper with his Princeton colleague Alan Krueger, which compared fast-food restaurants in two demographically similar communities on either side of the New Jersey-Pennsylvania border, one of which had recently seen a minimum-wage hike and one of which hadn’t.

AS: In the early days, there was skepticism about the empirical approach to economics. So every time you selected a new research project, you weren't just trying to answer an economics problem; you were also, in a sense, establishing the credibility of the approach. How did you select problems then? Was there a structure that you recognized as possibly lending itself to natural experiment?

Card: I think that the natural-experiment thing — there was really a brief period where that was novel, to tell you the truth. Maybe 1989 to 1992 or 3. I did this paper on the Mariel boatlift, which was cited by the committee. But to tell you the truth, that was a very modest paper. I never presented it anywhere, and it's in a very modest journal. So I never thought of that paper as going anywhere [laughs].

What happened was, it became more and more well understood that in order to make a claim of causality even from a natural-experiment setting, you had to have a fair amount of information from before the experiment took place to validate or verify that the group that you were calling the treatment group and the group that you were calling the control group actually were behaving the same.

That was a weakness of the project that Alan Krueger and I did. We had restaurants in New Jersey and Pennsylvania. We knew the minimum wage was going to increase — or we thought we knew that; it wasn't entirely clear at the time — but we surveyed the restaurants before, and then the minimum wage went up, and we surveyed them after, and that was good.

But we didn't really have multiple surveys from before to show that in the absence of the minimum wage, New Jersey and Pennsylvania restaurants had tracked each other for a long time. And these days, that's better understood. At Amazon for instance, people are doing intervention analyses of this type. They would normally look at what they call pre-trend analysis, make sure that the treatment group and the control group are trending the same beforehand.

I think there are 1,000 questions in economics that have been open forever. Sometimes new datasets come along. That's been happening a lot in labor economics: huge administrative datasets have become available, richer and richer, and now we're getting datasets that are created by these tech firms. So my usual thing is, I think, that's a dataset that maybe we can answer this old question on. That’s more my approach.

That's why being at Amazon has been great .... A lot of people have substantive questions they're trying to analyze with data, and they're kind of stuck in places, so there's a need for new methodologies.
Guido Imbens

Imbens: I come from a slightly different perspective. Most of my work has come from listening to people like David and Josh and seeing what type of problems they're working on, what type of methods they're using, and seeing if there's something to be added there — if there’s some way of improving the methods or places where maybe they're stuck, but listening to the people actually doing the empirical work rather than starting with the substantive questions.

That's why being at Amazon has been great, from my perspective. A lot of people have substantive questions they're trying to analyze with data, and they're kind of stuck in places, so there's a need for new methodologies. It's been a very fertile environment for me to come up with new research.

AS: Methodologically, what are some of the outstanding questions that interest you both?

Imbens: Well, one of the things is experimental design in complex environments. A lot of the experimental designs we’re using at the moment still come fairly directly from biomedical settings. We have a population, we randomize them into a treatment group and a control group, and then we compare outcomes for the two groups.

But in a lot of the settings we’re interested in at Amazon, there are very complex interactions between the units and their experiences, and dealing with that is very challenging. There are lots of special cases where we know somewhat what to do, but there are lots of cases where we don't know exactly what to do, and we need to do more complex experiments to get the answers to the questions we're interested in.

Double randomization — original color scheme.jpeg
An example of what Imbens calls “experimental design in complex environments”. In this illustration, each of five viewers is shown promotions for eight different Prime Video shows. Some of those promotions contain extra information, indicated in the image by star ratings (the “treatment”). This design helps determine whether the treatment affects viewing habits (the viewer experiment) but also helps identify spillover effects, in which participation in the viewer experiment influences the viewer’s behavior in other contexts.

The second thing is, we do a lot of these experiments, but often the experiments are relatively small. They’re small in duration, and they’re small in size relative to the overall population. You know, it goes back to the paper we mentioned before, combining this observational-study data with experimental data. That raises a lot of interesting methodological challenges that I spend a lot of time thinking about these days.

AS: I wondered if in the same way that in that early paper you were looking at survey data and population data, there's a way that natural experiments and economic field experiments can reinforce each other or give you a more reliable signal than you can get from either alone.

Card: There's one thing that people do; I've done a few of these myself. It's called meta analysis. It's a technique where you take results from different studies and try and put them into a statistical model. In a way it's comparable to work Guido has done at Amazon, where you take a series of actual experiments, A/B experiments done in Weblab, and basically combine them and say, “Okay, these aren't exactly the same products and the same conditions, but there's enough comparability that maybe I can build a model and use the information from the whole set to help inform what we're learning from any given one.”

And you can do that in studies in economics. For example, I’ve done one on training programs. There are many of these training programs. Each of them — exactly as Guido was saying — is often quite small. And there are weird conditions: sometimes it's only young males or young females that are in the experiment, or they don't have very long follow-up, or sometimes the labor market is really strong, and other times it's really weak. So you can try and build a model of the outcome you get from any given study and then try and see if there are any systematic patterns there.

Imbens: We do all these experiments, but often we kind of do them once, and then we put them aside. There's a lot of information over the years built up in all these experiments we've done, and finding more of these meta-analysis-type ways of combining them and exploiting all the information we have collected there — I think it's a very promising way to go.

AS: How can empirical methods complement theoretical approaches — model building of the kind that, in some sense, the early empirical research was reacting against?

Card: Normally, if you're building a model, there are a few key parameters, like you need to get some kind of an elasticity of what a customer will do if faced with a higher price or if offered a shorter, faster delivery speed versus slower delivery speed. And if you have those elasticities, then you can start building up a model.

If you have even a fairly complicated dynamic model, normally there's a relatively small number of these parameters, and the value of the model is to take this set of parameters and try and tell a bit richer story — not just how the customer responds to an offer of a faster delivery today but how that affects their future purchases and whether they come back and buy other products or whatever. But you need credible estimates of those elasticities. It's not helpful to build a model and then just pull numbers out of the air [laughs]. And that's why A/B experiments are so important at Amazon.

AS: I asked about outstanding methodological questions that you're interested in, but how about economic questions more broadly that you think could really benefit from an empirical approach?

Card: In my field [labor economics], we've begun to realize that different firms are setting different wages for the same kinds of workers. And we're starting to think about two issues related to that. One is, how do workers choose between jobs? Do they know about all the jobs out there? Do they just find out about some of the jobs? We're trying to figure out exactly why it's okay in the labor market for there to be multiple wages for a certain class of workers. Why don't all the workers immediately try to go to one job? This seems to be a very important phenomenon.

And on the other side of that, how do employers think about it? What are the benefits to employers of a higher wage or lower wage? Is it just the recruiting, or is it retention, or is it productivity? Is it longer-term goals? That's front and center in the research that I do outside of Amazon.

AS: I was curious if there were any cases where a problem presented itself, and at first you didn't think there was any way to get an empirical handle on it, and then you figured out that there was.

We're supposed to be social scientists who are trying to see what people are doing and the problems they confront and trying to analyze them. ... That's different than this old-fashioned Adam Smith view of the economy as a perfectly functioning tool that we're just supposed to admire.
David Card

Card: I saw a really interesting paper that was done by a PhD student who was visiting my center at Berkeley. In European football, there are a lot of non-white players, and fan racism is pretty pervasive. This guy noticed that during COVID, they played a lot of games with no fans. So he was able to compare the performance of the non-white and white players in the pre-COVID era and the COVID era, with and without fans, and showed that the non-white players did a little bit better. That's the kind of question where you’re saying, How are we ever going to study that? But if you're thinking and looking around, there's always some angle that might be useful.

Imbens: That's a very clever idea. I agree with David. If you just pay attention, there are a lot of things happening that allow you to answer important questions. Maybe fan insults in sports itself isn't that big a deal, but clearly, racism in the labor market and having people treated differently is a big problem. And here you get a very clear handle on an aspect of it. And once you show it's a problem there, it's very likely that it shows up in arguably substantively much more important settings where it's really hard to study.

In the Netherlands for a long time, they had a limit on the number of students who could go to medical school. And it wasn't decided by the medical schools themselves; they couldn't choose whom to admit. It was partly based on a lottery. At some point, someone used that to figure out how much access to medical school is actually worth. So essentially, you have two people who are both qualified to go to medical school; one gets lucky in the lottery; one doesn't. And it turns out you're giving the person who wins the lottery basically a lot of money. Obviously, in many professions we can't just randomly assign people to different types of jobs. But here you get a handle on the value of rationing that type of education.

Card: I think that's really important. You know, we're supposed to be social scientists who are trying to see what people are doing and the problems they confront and trying to analyze them. In a way, that's different than this sort of old-fashioned Adam Smith view of the economy as a perfectly functioning tool that we're just supposed to admire. That is a difference, I think.

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Team video https://youtu.be/zD_6Lzw8raE Key job responsibilities As an Applied Scientist II on this team, you will: - Drive end-to-end Machine Learning projects that have a high degree of ambiguity, scale, complexity. - Perform hands-on analysis and modeling of enormous data sets to develop insights that increase traffic monetization and merchandise sales, without compromising the shopper experience. - Build machine learning models, perform proof-of-concept, experiment, optimize, and deploy your models into production; work closely with software engineers to assist in deploying your ML models. - Run A/B experiments, gather data, and perform statistical analysis. - Establish scalable, efficient, automated processes for large-scale data analysis, machine-learning model development, model validation and serving. - Research new and innovative machine learning approaches.
US, WA, Bellevue
As a Principal Applied Scientist for Last Hundred Yards Automation, you will be at the forefront of developing AI and ML solutions that power our autonomous delivery robots. This role combines deep expertise in machine learning, computer vision, and robotics to solve complex challenges in real-world autonomous navigation, obstacle detection, and dynamic path planning. You will work closely with robotics engineers, software developers, and product teams to research, design, and implement sophisticated algorithms that enable safe and efficient last-yard delivery operations. This position requires a unique blend of theoretical knowledge and practical implementation skills, with a focus on transforming research concepts into production-ready solutions that can operate reliably in diverse real-world environments. Key job responsibilities The Principal Applied Scientist will lead the development and implementation of advanced AI/ML models for autonomous navigation, focusing on critical areas such as real-time object detection, semantic scene understanding, and predictive movement planning. You will be responsible for designing and conducting experiments, analyzing complex datasets, and developing novel algorithms to improve robot performance and reliability. The role involves collaborating with cross-functional teams to integrate ML solutions into the robotics platform, optimizing model performance for edge computing, and establishing metrics for continuous improvement. You will also mentor junior scientists, contribute to research publications, and stay current with latest developments in the field. Key activities include developing robust ML pipelines, implementing state-of-the-art deep learning architectures, and creating innovative solutions for challenging problems such as adverse weather navigation, multi-robot coordination, and human-robot interaction. Success in this role requires balancing research excellence with practical implementation, while maintaining a strong focus on safety and reliability in autonomous systems. About the team LMDA (Last Mile Delivery Automation) is a automation system designed to revolutionize the final phase of package delivery, focusing specifically on the last hundred yards from delivery vehicle to customer doorstep. The system integrates autonomous robots equipped with advanced AI/ML algorithms, real-time navigation capabilities, and smart obstacle avoidance technology to efficiently transport packages to their final destination. These robots are designed to navigate various terrains, including sidewalks, building entrances, and residential complexes, while adhering to local safety regulations and maintaining secure delivery protocols. LMDA incorporates cloud-based fleet management, real-time tracking, and dynamic route optimization to ensure seamless coordination between delivery vehicles and robots. The system features a user-friendly interface for both delivery personnel and customers, providing live tracking, delivery notifications, and interactive robot communication. As labor costs rise and delivery volumes increase, LMDA represents a scalable, cost-effective solution that addresses the growing challenges of last-mile delivery while significantly improving operational efficiency and customer satisfaction.
JP, 13, Tokyo
Are you a Graduate Student interested in machine learning, natural language processing, computer vision, automated reasoning, robotics? We are looking for skilled scientists capable of putting theory into practice through experimentation and invention, leveraging science techniques and implementing systems to work on massive datasets in an effort to tackle never-before-solved problems. A successful candidate will be a self-starter comfortable with ambiguity, strong attention to detail, and the ability to work in a fast-paced, ever-changing environment. As an Applied Scientist, you will own the design and development of end-to-end systems. You’ll have the opportunity to create technical roadmaps, and drive production level projects that will support Amazon Science. You will work closely with Amazon scientists, and other science interns to develop solutions and deploy them into production. The ideal scientist must have the ability to work with diverse groups of people and cross-functional teams to solve complex business problems. Key job responsibilities Amazon Science gives insight into the company’s approach to customer-obsessed scientific innovation. Amazon fundamentally believes that scientific innovation is essential to being the most customer-centric company in the world. It’s the company’s ability to have an impact at scale that allows us to attract some of the brightest minds in artificial intelligence and related fields. Amazon Scientist use our working backwards method to enrich the way we live and work. A day in the life Come teach us a few things, and we’ll teach you a few things as we navigate the most customer-centric company on Earth.
US, NY, New York
At Amazon Selection and Catalog Systems (ASCS), our mission is to power the online buying experience for customers worldwide so they can find, discover, and buy any product they want. We innovate on behalf of our customers to ensure uniqueness and consistency of product identity and to infer relationships between products in Amazon Catalog to drive the selection gateway for the search and browse experiences on the website. We're solving a fundamental AI challenge: establishing product identity and relationships at unprecedented scale. Using Generative AI, Visual Language Models (VLMs), and multimodal reasoning, we determine what makes each product unique and how products relate to one another across Amazon's catalog. The scale is staggering: billions of products, petabytes of multimodal data, millions of sellers, dozens of languages, and infinite product diversity—from electronics to groceries to digital content. The research challenges are immense. GenAI and VLMs hold transformative promise for catalog understanding, but we operate where traditional methods fail: ambiguous problem spaces, incomplete and noisy data, inherent uncertainty, reasoning across both images and textual data, and explaining decisions at scale. Establishing product identities and groupings requires sophisticated models that reason across text, images, and structured data—while maintaining accuracy and trust for high-stakes business decisions affecting millions of customers daily. Amazon's Item and Relationship Platform group is looking for an innovative and customer-focused applied scientist to help us make the world's best product catalog even better. In this role, you will partner with technology and business leaders to build new state-of-the-art algorithms, models, and services to infer product-to-product relationships that matter to our customers. You will pioneer advanced GenAI solutions that power next-generation agentic shopping experiences, working in a collaborative environment where you can experiment with massive data from the world's largest product catalog, tackle problems at the frontier of AI research, rapidly implement and deploy your algorithmic ideas at scale, across millions of customers. Key job responsibilities * Formulate novel research problems at the intersection of GenAI, multimodal learning, and large-scale information retrieval—translating ambiguous business challenges into tractable scientific frameworks * Design and implement leading models leveraging VLMs, foundation models, and agentic architectures to solve product identity, relationship inference, and catalog understanding at billion-product scale * Pioneer explainable AI methodologies that balance model performance with scalability requirements for production systems impacting millions of daily customer decisions * Own end-to-end ML pipelines from research ideation to production deployment—processing petabytes of multimodal data with rigorous evaluation frameworks * Define research roadmaps aligned with business priorities, balancing foundational research with incremental product improvements * Mentor peer scientists and engineers on advanced ML techniques, experimental design, and scientific rigor—building organizational capability in GenAI and multimodal AI * Represent the team in the broader science community—publishing findings, delivering tech talks, and staying at the forefront of GenAI, VLM, and agentic system research